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Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes

by Møller, Daniél V. , Perna, Eduardo , Melenovský, Vojtěch , Sharma, Kavita , Abhayaratna, Walter , Davies, Melanie J. , Liisberg, Karoline , Von Lewinski, Dirk , Kosiborod, Mikhail N. , Fu, Michael , Ahmed, Fozia Z. , Schou, Morten , Butler, Javed , Senni, Michele , Ezekowitz, Justin A. , Chopra, Vijay , Hovingh, G. Kees , Wolf, Dennis , Petrie, Mark C. , Jensen, Thomas J. , Shah, Sanjiv J. , Lindegaard, Marie L. , Ito, Hiroshi , Treppendahl, Marianne B. , Núñez, Julio , Borlaug, Barry A. , Merkely, Bela , Lelonek, Małgorzata , Ben-Gal, Tuvia , van der Meer, Peter , Kitzman, Dalane W. , Verma, Subodh

in administration & dosage / adverse effects / Analysis of covariance / Antidiabetics / Body weight loss / C-reactive protein / Cardiology / Cardiology General / Cardiomyopathy / Clinical Medicine / complications / Congestive heart failure / Diabetes / Diabetes Mellitus / Diabetes mellitus (non-insulin dependent) / Diabetes Mellitus, Type 2 - drug therapy / Diabetes Mellitus, Type 2 - etiology / Diabetic retinopathy / Double-Blind Method / drug therapy / Ejection fraction / Endocrinology / etiology / Gastrointestinal surgery / Glucagon-Like Peptide-1 Receptor Agonists / Glucagon-Like Peptide-1 Receptor Agonists - administration & dosage / Glucagon-Like Peptide-1 Receptor Agonists - adverse effects / Glucagon-Like Peptide-1 Receptor Agonists - therapeutic use / Glucagon-Like Peptides / Glucagon-Like Peptides - administration & dosage / Glucagon-Like Peptides - adverse effects / Glucagon-Like Peptides - therapeutic use / Glucose / Heart Failure / Heart Failure - drug therapy / Heart Failure - etiology / Humans / Intravenous therapy / Klinisk medicin / Missing data / Obesity / Obesity - complications / Obesity - drug therapy / Patients / Peptides / Placebos / Statistical analysis / Stroke Volume / therapeutic use / Type 2 / Weight control

2024

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Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes

2024

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Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes

2024

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Journal Article

Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes

Møller, Daniél V.,

Perna, Eduardo,

Melenovský, Vojtěch,

Sharma, Kavita,

Abhayaratna, Walter,

Davies, Melanie J.,

Liisberg, Karoline,

Von Lewinski, Dirk,

Kosiborod, Mikhail N.,

Fu, Michael,

Ahmed, Fozia Z.,

Schou, Morten,

Butler, Javed,

Senni, Michele,

Ezekowitz, Justin A.,

Chopra, Vijay,

Hovingh, G. Kees,

Wolf, Dennis,

Petrie, Mark C.,

Jensen, Thomas J.,

Shah, Sanjiv J.,

Lindegaard, Marie L.,

Ito, Hiroshi,

Treppendahl, Marianne B.,

Núñez, Julio,

Borlaug, Barry A.,

Merkely, Bela,

Lelonek, Małgorzata,

Ben-Gal, Tuvia,

van der Meer, Peter,

Kitzman, Dalane W.,

Verma, Subodh

2024

Overview

Among patients with obesity-related heart failure with preserved ejection fraction and type 2 diabetes, semaglutide produced greater reductions in symptoms, physical limitations, and body weight than placebo at 1 year.

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Publisher

Massachusetts Medical Society

Subject

administration & dosage

/ adverse effects

/ Analysis of covariance