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Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study
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Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study
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Journal Article
Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study
2024
Overview
The n-back task is a widely used paradigm to assess working memory and is commonly applied in research on age-related cognitive decline. However, studies utilizing functional near-infrared spectroscopy (fNIRS) to explore this area are limited.
This study aims to investigate age-related differences in brain activation during the n-back task using fNIRS.
fNIRS data were collected from 18 elderly and 19 young participants while performing different n-back tasks. Brain activation patterns and peripheral performance were compared between the two groups.
Significant differences in brain activation patterns were observed between elderly and young participants. Under the 3-back condition, the older group exhibited reduced activation in brain regions adjacent to prefrontal cognitive areas compared to the younger group. Additionally, the older group's performance plateaued at the 2-back level, along with a decline in prefrontal activation.
These findings may suggest potential markers for cognitive decline, providing a new target for future screening.
Publisher
Frontiers Media S.A
Subject
