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SEA-AD is a multimodal cellular atlas and resource for Alzheimer’s disease

by Larson, Eric B. , Ng, Lydia , Mollenkopf, Tyler , Crane, Paul K. , Hodge, Rebecca D. , Gabitto, Mariano I. , Hawrylycz, Michael , Travaglini, Kyle J. , Close, Jennie L. , Keene, C. Dirk , Lein, Ed S. , Long, Brian , Grabowski, Thomas J. , Gatto, Nicole M. , Kaplan, Eitan S. , Miller, Jeremy A. , Mufti, Shoaib

in 13/51 / 14/32 / 38/39 / 38/91 / 631/378/1689/1283 / 692/699/375/365/1283 / 706/648/697/129 / Aging / Alzheimer's disease / Biomedical and Life Sciences / Brain research / Comment / Dementia / Disease / Genomics / Life Sciences / Metadata / Neuropathology / Pathology / Peptides / Quantitative analysis / Tissues

2024

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2024

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2024

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Journal Article

SEA-AD is a multimodal cellular atlas and resource for Alzheimer’s disease

Larson, Eric B.,

Ng, Lydia,

Mollenkopf, Tyler,

Crane, Paul K.,

Hodge, Rebecca D.,

Gabitto, Mariano I.,

Hawrylycz, Michael,

Travaglini, Kyle J.,

Close, Jennie L.,

Keene, C. Dirk,

Lein, Ed S.,

Long, Brian,

Grabowski, Thomas J.,

Gatto, Nicole M.,

Kaplan, Eitan S.,

Miller, Jeremy A.,

Mufti, Shoaib

2024

Overview

The Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD) is a multifaceted open-data resource that is designed to identify cellular and molecular pathologies that underlie Alzheimer’s disease. Integrating neuropathology, single-cell and spatial genomics, and longitudinal clinical metadata, SEA-AD is a unique resource for studying the pathogenesis of Alzheimer’s disease and related dementias.

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Publisher

Nature Publishing Group US,Nature Publishing Group

Subject

13/51

/ 14/32

/ 38/39

/ 38/91

/ 631/378/1689/1283

/ 692/699/375/365/1283

/ 706/648/697/129