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An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
by
Karnoukhova, Valentina A
, Kravchenko, Angelina N
, Makhova, Nina N
, Izmest’ev, Alexei N
, Sigay, Natalya V
, Kachala, Vadim V
, Shashkov, Alexander S
, Serkov, Sergei A
, Zanin, Igor E
, Gazieva, Galina A
in
azomethine ylides
/ Chemistry
/ cycloaddition
/ diastereoselectivity
/ Full Research Paper
/ nitrogen heterocycles
/ spiro compounds
2016
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An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
by
Karnoukhova, Valentina A
, Kravchenko, Angelina N
, Makhova, Nina N
, Izmest’ev, Alexei N
, Sigay, Natalya V
, Kachala, Vadim V
, Shashkov, Alexander S
, Serkov, Sergei A
, Zanin, Igor E
, Gazieva, Galina A
in
azomethine ylides
/ Chemistry
/ cycloaddition
/ diastereoselectivity
/ Full Research Paper
/ nitrogen heterocycles
/ spiro compounds
2016
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An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
by
Karnoukhova, Valentina A
, Kravchenko, Angelina N
, Makhova, Nina N
, Izmest’ev, Alexei N
, Sigay, Natalya V
, Kachala, Vadim V
, Shashkov, Alexander S
, Serkov, Sergei A
, Zanin, Igor E
, Gazieva, Galina A
in
azomethine ylides
/ Chemistry
/ cycloaddition
/ diastereoselectivity
/ Full Research Paper
/ nitrogen heterocycles
/ spiro compounds
2016
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An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
Journal Article
An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
2016
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Overview
An effective and highly regio- and diastereoselective one-pot method for the synthesis of new polynuclear dispiroheterocyclic systems with five stereogenic centers (dispiro[imidazo[4,5- e ]thiazolo[3,2- b ]-1,2,4-triazine-6,3′-pyrrolidine-2′,3′′-indoles]) comprising pyrrolidinyloxindole and imidazo[4,5- e ]thiazolo[3,2- b ]-1,2,4-triazine moieties has been developed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from isatin derivatives and sarcosine to 6-benzylideneimidazo[4,5- e ]thiazolo[3,2- b ]-1,2,4-triazine-2,7-diones.
Publisher
Beilstein-Institut zur Föerderung der Chemischen Wissenschaften,Beilstein-Institut
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