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Treatment Strategy for Rifampin-Susceptible Tuberculosis

by Avihingsanon, Anchalee , Sekaggya-Wiltshire, Christine , Pokharkar, Yogesh , Burhan, Erlina , Crook, Angela M. , Djaharuddin, Irawaty , Dalay, Victoria B. , Nunn, Andrew J. , Suresh, Celina , Lee, Shu Ling , Lu, Qingshu , Veto, Rholine S. , Ruslami, Rovina , Sarin, Rohit , Sugiri, Jani J.R. , Kusmiati, Tutik , Chew, Ka Lip , Papineni, Padmasayee , Balanag, Vincent M. , Cousins, Christopher , Paton, Nicholas I.

in Adverse events / Antitubercular Agents - adverse effects / Antitubercular Agents - therapeutic use / Clinical trials / Diarylquinolines - adverse effects / Diarylquinolines - therapeutic use / Drug Administration Schedule / Drug dosages / Drug resistance / Drug Therapy, Combination / Ethambutol / Ethambutol - adverse effects / Ethambutol - therapeutic use / Genomes / Global Health / Humans / Infectious Disease / Infectious Disease General / Isoniazid / Isoniazid - adverse effects / Isoniazid - therapeutic use / Linezolid / Linezolid - adverse effects / Linezolid - therapeutic use / Medical research / Medical treatment / Pyrazinamide / Pyrazinamide - adverse effects / Pyrazinamide - therapeutic use / Rifampin / Rifampin - adverse effects / Rifampin - therapeutic use / Statistical analysis / Treatment Outcome / Tuberculosis / Tuberculosis, Multidrug-Resistant - drug therapy / Tuberculosis, Pulmonary - complications / Tuberculosis, Pulmonary - drug therapy

2023

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2023

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2023

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Journal Article

Treatment Strategy for Rifampin-Susceptible Tuberculosis

Avihingsanon, Anchalee,

Sekaggya-Wiltshire, Christine,

Pokharkar, Yogesh,

Burhan, Erlina,

Crook, Angela M.,

Djaharuddin, Irawaty,

Dalay, Victoria B.,

Nunn, Andrew J.,

Suresh, Celina,

Lee, Shu Ling,

Lu, Qingshu,

Veto, Rholine S.,

Ruslami, Rovina,

Sarin, Rohit,

Sugiri, Jani J.R.,

Kusmiati, Tutik,

Chew, Ka Lip,

Papineni, Padmasayee,

Balanag, Vincent M.,

Cousins, Christopher,

Paton, Nicholas I.

2023

Overview

Treatment for tuberculosis, a leading cause of death worldwide, typically involves 6 months of continuous therapy. In this trial, a strategy involving shorter initial treatment was noninferior to standard treatment.

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Publisher

Massachusetts Medical Society

Subject

Adverse events

/ Antitubercular Agents - adverse effects

/ Antitubercular Agents - therapeutic use

/ Clinical trials

/ Diarylquinolines - adverse effects

/ Diarylquinolines - therapeutic use

/ Drug Administration Schedule