Asset Details
Do you wish to reserve the book?
When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
Do you wish to request the book?
When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
2018
Overview
As a substantial part of the brain tumor microenvironment (TME), glioma-associated microglia/macrophages (GAMs) have an emerging role in tumor progression and in controlling anti-tumor immune responses. We review challenges and improvements of cell models and highlight the contribution of this highly plastic cell population to an immunosuppressive TME, besides their well-known functional role regarding glioma cell invasion and angiogenesis. Finally, we summarize first therapeutic interventions to target GAMs and their effect on the immunobiology of gliomas, focusing on their interaction with T cells.
Publisher
MDPI AG,MDPI
