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Divisive normalization unifies disparate response signatures throughout the human visual hierarchy
by
Dumoulin, Serge O.
, Knapen, Tomas
, Aqil, Marco
in
Biological Sciences
/ Computation
/ Functional magnetic resonance imaging
/ Humans
/ Information processing
/ Magnetic Resonance Imaging - methods
/ Mathematical models
/ Models, Neurological
/ Neurons - physiology
/ Neuroscience
/ Photic Stimulation - methods
/ Receptive field
/ Signatures
/ Visual Cortex - physiology
/ Visual observation
2021
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Divisive normalization unifies disparate response signatures throughout the human visual hierarchy
by
Dumoulin, Serge O.
, Knapen, Tomas
, Aqil, Marco
in
Biological Sciences
/ Computation
/ Functional magnetic resonance imaging
/ Humans
/ Information processing
/ Magnetic Resonance Imaging - methods
/ Mathematical models
/ Models, Neurological
/ Neurons - physiology
/ Neuroscience
/ Photic Stimulation - methods
/ Receptive field
/ Signatures
/ Visual Cortex - physiology
/ Visual observation
2021
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Do you wish to request the book?
Divisive normalization unifies disparate response signatures throughout the human visual hierarchy
by
Dumoulin, Serge O.
, Knapen, Tomas
, Aqil, Marco
in
Biological Sciences
/ Computation
/ Functional magnetic resonance imaging
/ Humans
/ Information processing
/ Magnetic Resonance Imaging - methods
/ Mathematical models
/ Models, Neurological
/ Neurons - physiology
/ Neuroscience
/ Photic Stimulation - methods
/ Receptive field
/ Signatures
/ Visual Cortex - physiology
/ Visual observation
2021
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Divisive normalization unifies disparate response signatures throughout the human visual hierarchy
Journal Article
Divisive normalization unifies disparate response signatures throughout the human visual hierarchy
2021
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Overview
Neural processing is hypothesized to apply the same mathematical operations in a variety of contexts, implementing so-called canonical neural computations. Divisive normalization (DN) is considered a prime candidate for a canonical computation. Here, we propose a population receptive field (pRF) model based on DN and evaluate it using ultra-high-field functional MRI (fMRI). The DN model parsimoniously captures seemingly disparate response signatures with a single computation, superseding existing pRF models in both performance and biological plausibility. We observe systematic variations in specific DN model parameters across the visual hierarchy and show how they relate to differences in response modulation and visuospatial information integration. The DN model delivers a unifying framework for visuospatial responses throughout the human visual hierarchy and provides insights into its underlying information-encoding computations. These findings extend the role of DN as a canonical computation to neuronal populations throughout the human visual hierarchy.
Publisher
National Academy of Sciences
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