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Central nervous system involvement in systemic connective tissue diseases
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Journal Article
Central nervous system involvement in systemic connective tissue diseases
2006
Overview
Systemic connective tissue diseases can affect the brain, meninges, spinal cord, cranial and peripheral nerves. Different pathogenic mechanisms, particularly autoantibody or T-cell mediated lesions, appear to be involved. The neurological manifestations of the connective tissue diseases and their diagnostic possibilities including newer imaging techniques are reviewed. Early recognition of neurological abnormalities can help in the differential diagnosis and in defining the underlying disease in order to initiate treatment and prevent progression of lesion or cognitive function loss.
Publisher
Elsevier B.V,Elsevier Science,Elsevier Limited
Subject
Biological and medical sciences
/ Central Nervous System Diseases - diagnosis
/ Central Nervous System Diseases - etiology
/ Central Nervous System Diseases - immunology
/ Connective Tissue Diseases - complications
/ Connective Tissue Diseases - immunology
/ Demyelinating autoimmune diseases
/ Disease
/ Humans
/ Lupus
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
