Asset Details
Do you wish to reserve the book?
Application of the amide proton transfer-weighted imaging and diffusion kurtosis imaging in the study of cervical cancer
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Application of the amide proton transfer-weighted imaging and diffusion kurtosis imaging in the study of cervical cancer
Do you wish to request the book?
Application of the amide proton transfer-weighted imaging and diffusion kurtosis imaging in the study of cervical cancer
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Application of the amide proton transfer-weighted imaging and diffusion kurtosis imaging in the study of cervical cancer
2020
Overview
ObjectivesTo analyze the value of amide proton transfer-weighted imaging (APTWI) and diffusion kurtosis imaging (DKI) in differentiating cervical cancer (CC) pathological type, grade, and stage.MethodsOne hundred and twelve women underwent pelvic APTWI and DKI. The magnetization transfer ratio asymmetry (MTRasym, 3.5 ppm), apparent kurtosis coefficient (Kapp), and non-Gaussian diffusion coefficient (Dapp) were calculated by histological subtype, grade, and stage. The differences, efficacy, and correlation between parameters were determined.ResultsThe MTRasym(3.5 ppm) and Dapp values of the adenocarcinoma (CA) group were higher than those of the cervical squamous carcinoma (CSC) group, while the Kapp values were lower than those of the CSC group. The MTRasym(3.5 ppm) and Kapp values of the high-grade group were higher than those of the low-grade group, while the Dapp values were lower than those of the low-grade group. The Dapp values of the advanced-stage group were lower than those of the early-stage group, while the Kapp values were greater than those of the early-stage group. The Kapp showed the highest efficacy in differentiating CSC and CA, high- and low-grade CC, and advanced- and early-stage CC. In the CSC and CA groups, both the Kapp and Dapp were highly correlated with pathological grade, and the MTRasym(3.5 ppm) was weakly correlated with pathological grade. The Kapp, Dapp, and MTRasym(3.5 ppm) were all weakly correlated with pathological stage.ConclusionBoth DKI and APTWI can be used in preliminary evaluations of CC, but DKI has advantages in the identification of pathological type, grade, and stage.Key Points• PTWI and DKI provide new information regarding cervical cancer.• MTRasym(3.5 ppm), Dapp, and Kappare valid parameters to characterize tissue microstructure.• DKI is superior to APTWI in the study of cervical cancer.
Publisher
Springer Nature B.V
Subject
