Asset Details
Do you wish to reserve the book?
The mesoporosity of microparticles spray dried from trehalose and nanoparticle hydroxyapatite depends on the ratio of nanoparticles to sugar and nanoparticle surface charge
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
The mesoporosity of microparticles spray dried from trehalose and nanoparticle hydroxyapatite depends on the ratio of nanoparticles to sugar and nanoparticle surface charge
Do you wish to request the book?
The mesoporosity of microparticles spray dried from trehalose and nanoparticle hydroxyapatite depends on the ratio of nanoparticles to sugar and nanoparticle surface charge
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
The mesoporosity of microparticles spray dried from trehalose and nanoparticle hydroxyapatite depends on the ratio of nanoparticles to sugar and nanoparticle surface charge
2010
Overview
The ratio of hydroxyapatite (HA) nanoparticles (NP) to trehalose in composite microparticle (MP) vaccine vehicles by determining inter-nanoparticle space potentially influences antigen release. Mercury porosimetry and gas adsorption analysis have been used quantify this space. Larger pores are present in MPs spray dried solely from nanoparticle gel compared with MPs spray dried from nanoparticle colloid which have less inter-nanoparticle volume. This is attributed to tighter nanoparticle packing caused by citrate modification of their surface charge. The pore size distributions (PSD) for MP where the trehalose has been eliminated by combustion generally broaden and shifts to higher values with increasing initial trehalose content. Modal pore size, for gel derived MPs is comparable to modal NP width below 30% initial trehalose content and approximates to modal NP length (~50 nm) at 60% initial trehalose content. For colloidally derived MPs this never exceeds the modal NP width. Pore-sizes are comparable, to surface inter-nanoparticle spacings observed by SEM.
Publisher
Springer US,Springer,Springer Nature B.V
Subject
Biological and medical sciences
/ Biomedical Engineering and Bioengineering
/ Ceramics
/ Chemistry and Materials Science
/ Coated Materials, Biocompatible - chemistry
/ Drug Carriers - chemical synthesis
/ Electrophysiological Phenomena
/ Glass
/ Microscopy, Electron, Scanning
/ Pharmaceutical technology. Pharmaceutical industry
/ Pharmacology. Drug treatments
/ Porosity
/ Powders - chemical synthesis
/ Pressure
