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Serum levels of folate, lycopene, β-carotene, retinol and vitamin E and prostate cancer risk
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Serum levels of folate, lycopene, β-carotene, retinol and vitamin E and prostate cancer risk
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Journal Article
Serum levels of folate, lycopene, β-carotene, retinol and vitamin E and prostate cancer risk
2010
Overview
Previous studies relating increased serum levels of folate and fat-soluble vitamins to prostate cancer risk have variously shown null associations or to either decrease or increase the risk of developing prostate cancer. Prospective studies of serum folate levels have been reported to show a null association and increased serum levels to either decrease or increase the risk of subsequently developing prostate cancer. Similarly, serum β-carotene and lycopene levels have either been reported to be inversely correlated or not associated with prostate cancer risk. Using a prospective nested case-control study design, which minimized the possibility of disease effects on serum-vitamin concentrations, we report null associations for serum concentrations of folate, lycopene, β-carotene, vitamin A and vitamin E, and subsequent development of prostate cancer.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
/ Aged
/ Biological and medical sciences
/ blood
/ Carotene
/ Fundamental and applied biological sciences. Psychology
/ Humans
/ Lycopene
/ Male
/ Medicine
/ Nephrology. Urinary tract diseases
/ Prostatic Neoplasms - epidemiology
/ Risk
/ Tumors of the urinary system
/ Urinary tract. Prostate gland
/ validity
/ Vertebrates: anatomy and physiology, studies on body, several organs or systems
/ Vitamins
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