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Triglyceride Deposit Cardiomyovasculopathy
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Journal Article
Triglyceride Deposit Cardiomyovasculopathy
2008
Overview
To the Editor:
A 41-year-old man was admitted to our hospital with ventricular tachycardia in 2003. Biopsy specimens obtained from the right ventricle showed neutral lipid deposition in cardiomyocytes. In 2004, the patient had catecholamine-dependent congestive heart failure, and a left ventricular assist system was implanted. Skeletal-muscle atrophy in the arms became evident, and staining of biopsy specimens with oil red O showed droplets of predominantly type I fibers (Figure 1A). Levels of plasma lipids and carnitine were normal.
In June 2007, the patient underwent cardiac transplantation. Microscopical examination of the explanted heart revealed numerous vacuoles that stained positive for . . .
Publisher
Massachusetts Medical Society
