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Kampo Medicine Promotes Early Recovery From Coronavirus Disease 2019-Related Olfactory Dysfunction: A Retrospective Observational Study
by
Kikuchi, Akiko
, Ishii, Tadashi
, Saito, Natsumi
, Takayama, Shin
, Ono, Rie
, Ohsawa, Minoru
, Suzuki, Satoko
, Arita, Ryutaro
in
Anosmia
/ Asthma
/ coronavirus disease 2019
/ Coronaviruses
/ COVID-19
/ early recovery
/ Ethics
/ Fever
/ Health insurance
/ kampo
/ Observational studies
/ Olfaction
/ olfactory dysfunction
/ Patients
/ Pharmacology
/ Prescription drugs
/ promotes
/ Quality of life
/ Regression analysis
/ Severe acute respiratory syndrome coronavirus 2
/ Traditional medicine
2022
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Kampo Medicine Promotes Early Recovery From Coronavirus Disease 2019-Related Olfactory Dysfunction: A Retrospective Observational Study
by
Kikuchi, Akiko
, Ishii, Tadashi
, Saito, Natsumi
, Takayama, Shin
, Ono, Rie
, Ohsawa, Minoru
, Suzuki, Satoko
, Arita, Ryutaro
in
Anosmia
/ Asthma
/ coronavirus disease 2019
/ Coronaviruses
/ COVID-19
/ early recovery
/ Ethics
/ Fever
/ Health insurance
/ kampo
/ Observational studies
/ Olfaction
/ olfactory dysfunction
/ Patients
/ Pharmacology
/ Prescription drugs
/ promotes
/ Quality of life
/ Regression analysis
/ Severe acute respiratory syndrome coronavirus 2
/ Traditional medicine
2022
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Do you wish to request the book?
Kampo Medicine Promotes Early Recovery From Coronavirus Disease 2019-Related Olfactory Dysfunction: A Retrospective Observational Study
by
Kikuchi, Akiko
, Ishii, Tadashi
, Saito, Natsumi
, Takayama, Shin
, Ono, Rie
, Ohsawa, Minoru
, Suzuki, Satoko
, Arita, Ryutaro
in
Anosmia
/ Asthma
/ coronavirus disease 2019
/ Coronaviruses
/ COVID-19
/ early recovery
/ Ethics
/ Fever
/ Health insurance
/ kampo
/ Observational studies
/ Olfaction
/ olfactory dysfunction
/ Patients
/ Pharmacology
/ Prescription drugs
/ promotes
/ Quality of life
/ Regression analysis
/ Severe acute respiratory syndrome coronavirus 2
/ Traditional medicine
2022
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Kampo Medicine Promotes Early Recovery From Coronavirus Disease 2019-Related Olfactory Dysfunction: A Retrospective Observational Study
Journal Article
Kampo Medicine Promotes Early Recovery From Coronavirus Disease 2019-Related Olfactory Dysfunction: A Retrospective Observational Study
2022
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Overview
Background: Olfactory dysfunction is a common symptom in patients with coronavirus disease 2019, and it significantly deteriorates patients’ quality of life. Effective treatments remain unknown. Purpose: To assess the effect of Japanese traditional (Kampo) medicine on coronavirus disease 2019-related olfactory dysfunction. Study Design: Retrospective observational study. Methods: In total, 87 patients aged ≥18 years with coronavirus disease 2019 and severe dysosmia or anosmia (Numeric Rating Scale, ≥7) at isolation facilities in Miyagi Prefecture, Japan, were enrolled from October 2020 to March 2021. Patients were divided into the Kampo group ( N = 52) and the control group ( N = 35) based on the treatment received. Changes in Numeric Rating Scale scores were evaluated at the first visit and 2 weeks after. Results: The median reduction in the olfactory dysfunction score at both 1 and 2 weeks after the first visit was significantly greater in the Kampo group (6 and 8, respectively; p = 0.03) than in the control group (3 and 7, respectively; p = 0.04). We defined improvement in olfactory dysfunction as a median reduction in the olfactory dysfunction score of ≥5. Multiple logistic regression analysis demonstrated that only Kampo treatment was significantly associated with improvement in olfactory dysfunction. Conclusion: This study suggests that Kampo medication promotes early recovery from coronavirus disease 2019-related olfactory dysfunction.
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