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Heart in space: effect of the extraterrestrial environment on the cardiovascular system
by
Helm, Alexander
, Durante, Marco
, Hughson, Richard L
in
Analysis
/ Antioxidants - administration & dosage
/ Astronauts
/ Cardiopulmonary system
/ Cardiovascular Diseases - chemically induced
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - physiopathology
/ Cardiovascular Diseases - prevention & control
/ Cardiovascular system
/ Cardiovascular System - drug effects
/ Cardiovascular System - physiopathology
/ Cardiovascular System - radiation effects
/ Circulatory system
/ Cosmic Radiation - adverse effects
/ Cosmic rays
/ Dietary Supplements
/ Exercise
/ Extraterrestrial Environment
/ Health aspects
/ Heart function tests
/ Humans
/ Occupational Exposure - adverse effects
/ Occupational Exposure - prevention & control
/ Protective Factors
/ Radiation Exposure - adverse effects
/ Radiation Exposure - prevention & control
/ Radiation Injuries - etiology
/ Radiation Injuries - physiopathology
/ Radiation Injuries - prevention & control
/ Radiation Protection
/ Risk Assessment
/ Risk Factors
/ Weightlessness - adverse effects
/ Weightlessness Countermeasures
2018
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Heart in space: effect of the extraterrestrial environment on the cardiovascular system
by
Helm, Alexander
, Durante, Marco
, Hughson, Richard L
in
Analysis
/ Antioxidants - administration & dosage
/ Astronauts
/ Cardiopulmonary system
/ Cardiovascular Diseases - chemically induced
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - physiopathology
/ Cardiovascular Diseases - prevention & control
/ Cardiovascular system
/ Cardiovascular System - drug effects
/ Cardiovascular System - physiopathology
/ Cardiovascular System - radiation effects
/ Circulatory system
/ Cosmic Radiation - adverse effects
/ Cosmic rays
/ Dietary Supplements
/ Exercise
/ Extraterrestrial Environment
/ Health aspects
/ Heart function tests
/ Humans
/ Occupational Exposure - adverse effects
/ Occupational Exposure - prevention & control
/ Protective Factors
/ Radiation Exposure - adverse effects
/ Radiation Exposure - prevention & control
/ Radiation Injuries - etiology
/ Radiation Injuries - physiopathology
/ Radiation Injuries - prevention & control
/ Radiation Protection
/ Risk Assessment
/ Risk Factors
/ Weightlessness - adverse effects
/ Weightlessness Countermeasures
2018
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![Heart in space: effect of the extraterrestrial environment on the cardiovascular system](https://www.mbrl.ae/o/mbrl-theme/images/site-assets/generic/no-book-image.png)
Heart in space: effect of the extraterrestrial environment on the cardiovascular system
by
Helm, Alexander
, Durante, Marco
, Hughson, Richard L
in
Analysis
/ Antioxidants - administration & dosage
/ Astronauts
/ Cardiopulmonary system
/ Cardiovascular Diseases - chemically induced
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - physiopathology
/ Cardiovascular Diseases - prevention & control
/ Cardiovascular system
/ Cardiovascular System - drug effects
/ Cardiovascular System - physiopathology
/ Cardiovascular System - radiation effects
/ Circulatory system
/ Cosmic Radiation - adverse effects
/ Cosmic rays
/ Dietary Supplements
/ Exercise
/ Extraterrestrial Environment
/ Health aspects
/ Heart function tests
/ Humans
/ Occupational Exposure - adverse effects
/ Occupational Exposure - prevention & control
/ Protective Factors
/ Radiation Exposure - adverse effects
/ Radiation Exposure - prevention & control
/ Radiation Injuries - etiology
/ Radiation Injuries - physiopathology
/ Radiation Injuries - prevention & control
/ Radiation Protection
/ Risk Assessment
/ Risk Factors
/ Weightlessness - adverse effects
/ Weightlessness Countermeasures
2018
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Heart in space: effect of the extraterrestrial environment on the cardiovascular system
![Heart in space: effect of the extraterrestrial environment on the cardiovascular system](https://syndetics.com/index.aspx?isbn=/mc.gif&issn=1759-5002&client=MBRL&type=mbrl)
Journal Article
Heart in space: effect of the extraterrestrial environment on the cardiovascular system
2018
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Overview
National space agencies and private corporations aim at an extended presence of humans in space in the medium to long term. Together with currently suboptimal technology, microgravity and cosmic rays raise health concerns about deep-space exploration missions. Both of these physical factors affect the cardiovascular system, whose gravity-dependence is pronounced. Heart and vascular function are, therefore, susceptible to substantial changes in weightlessness. The altered cardiovascular function in space causes physiological problems in the postflight period. A compromised cardiovascular system can be excessively vulnerable to space radiation, synergistically resulting in increased damage. The space radiation dose is significantly lower than in patients undergoing radiotherapy, in whom cardiac damage is well-documented following cancer therapy in the thoracic region. Nevertheless, epidemiological findings suggest an increased risk of late cardiovascular disease even with low doses of radiation. Moreover, the peculiar biological effectiveness of heavy ions in cosmic rays might increase this risk substantially. However, whether radiation-induced cardiovascular effects have a threshold at low doses is still unclear. The main countermeasures to mitigate the effect of the space environment on cardiac function are physical exercise, antioxidants, nutraceuticals, and radiation shielding.
Publisher
Nature Publishing Group
Subject
/ Antioxidants - administration & dosage
/ Cardiovascular Diseases - chemically induced
/ Cardiovascular Diseases - etiology
/ Cardiovascular Diseases - physiopathology
/ Cardiovascular Diseases - prevention & control
/ Cardiovascular System - drug effects
/ Cardiovascular System - physiopathology
/ Cardiovascular System - radiation effects
/ Cosmic Radiation - adverse effects
/ Exercise
/ Extraterrestrial Environment
/ Humans
/ Occupational Exposure - adverse effects
/ Occupational Exposure - prevention & control
/ Radiation Exposure - adverse effects
/ Radiation Exposure - prevention & control
/ Radiation Injuries - etiology
/ Radiation Injuries - physiopathology
/ Radiation Injuries - prevention & control
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