Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

The Influence of Microenvironment on Survival of Intraportal Transplanted Islets

by Chen, Ya-hong , Mao, Xin-li , Zhang, Chen-yang , Ye, Li-ping , Li, Shao-wei , He, Sai-qin , Yan, Ling-ling

in Anti-inflammatory agents / Anticoagulants / Blood platelets / Clinical trials / Cytokines / Diabetes / Diabetes mellitus (insulin dependent) / Diabetes Mellitus, Type 1 - metabolism / Graft rejection / Humans / Hypoglycemia / Hypoxia / Immune response / Immunological tolerance / Immunology / Inflammation / inflammatory cytokine / instant blood / Insulin / Islet cells / islet transplantation / Islets of Langerhans / Islets of Langerhans Transplantation - adverse effects / Leukocytes / mediated inflammatory reaction / microenvironment / Microenvironments / Molecular weight / Neutrophils / Pancreas / Pancreatic islet transplantation / Reperfusion / Survival / therapeutic target / Therapeutic targets / Transplantation, Heterologous - adverse effects / Transplants & implants / Tumor necrosis factor-TNF

2022

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

The Influence of Microenvironment on Survival of Intraportal Transplanted Islets

by Chen, Ya-hong , Mao, Xin-li , Zhang, Chen-yang , Ye, Li-ping , Li, Shao-wei , He, Sai-qin , Yan, Ling-ling

2022

Confirm

Do you wish to request the book?

The Influence of Microenvironment on Survival of Intraportal Transplanted Islets

by Chen, Ya-hong , Mao, Xin-li , Zhang, Chen-yang , Ye, Li-ping , Li, Shao-wei , He, Sai-qin , Yan, Ling-ling

2022

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

The Influence of Microenvironment on Survival of Intraportal Transplanted Islets

Chen, Ya-hong,

Mao, Xin-li,

Zhang, Chen-yang,

Ye, Li-ping,

Li, Shao-wei,

He, Sai-qin,

Yan, Ling-ling

2022

Overview

Clinical islet transplantation has the potential to cure type 1 diabetes. Despite recent therapeutic success, it is still uncommon because transplanted islets are damaged by multiple challenges, including instant blood mediated inflammatory reaction (IBMIR), inflammatory cytokines, hypoxia/reperfusion injury, and immune rejection. The transplantation microenvironment plays a vital role especially in intraportal islet transplantation. The identification and targeting of pathways that function as “master regulators” during deleterious inflammatory events after transplantation, and the induction of immune tolerance, are necessary to improve the survival of transplanted islets. In this article, we attempt to provide an overview of the influence of microenvironment on the survival of transplanted islets, as well as possible therapeutic targets.

Share this book

Add to My Shelf

Publisher

Frontiers Media SA,Frontiers Media S.A

Subject

Anti-inflammatory agents

/ Diabetes mellitus (insulin dependent)