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Metabolic and structural impairment of skeletal muscle in heart failure
Metabolic and structural impairment of skeletal muscle in heart failure
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Metabolic and structural impairment of skeletal muscle in heart failure
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Metabolic and structural impairment of skeletal muscle in heart failure
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Metabolic and structural impairment of skeletal muscle in heart failure
Metabolic and structural impairment of skeletal muscle in heart failure
Journal Article

Metabolic and structural impairment of skeletal muscle in heart failure

2013
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Overview
Physiologic endurance exercise performance is primarily limited by cardiac function. In patients with heart failure, there is dissociation between cardiac performance and exercise capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal muscle function. The impact of heart failure upon skeletal muscle and exercise performance will be discussed with a focus on molecular, structural, and functional derangements in skeletal muscle of patients with heart failure.