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Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review
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Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review
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Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review
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Journal Article
Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review
2017
Overview
Bioactive compounds from natural sources, due to their widely-recognized benefits, have been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a very interesting potential. In this context, this review analyzes hydroxycinnamic acids and their derivatives as multifunctional ingredients for topical application, as well as the limitations associated with their use in cosmetic formulations. Hydroxycinnamic acids and their derivatives display antioxidant, anti-collagenase, anti-inflammatory, antimicrobial and anti-tyrosinase activities, as well as ultraviolet (UV) protective effects, suggesting that they can be exploited as anti-aging and anti-inflammatory agents, preservatives and hyperpigmentation-correcting ingredients. Due to their poor stability, easy degradation and oxidation, microencapsulation techniques have been employed for topical application, preventing them from degradation and enabling a sustained release. Based on the above findings, hydroxycinnamic acids present high cosmetic potential, but studies addressing the validation of their benefits in cosmetic formulations are still scarce. Furthermore, studies dealing with skin permeation are scarcely available and need to be conducted in order to predict the topical bioavailability of these compounds after application.
Publisher
MDPI AG,MDPI
Subject
/ Algae
/ Animals
/ Anti-Infective Agents - administration & dosage
/ Anti-Infective Agents - chemistry
/ Anti-Infective Agents - metabolism
/ Anti-Inflammatory Agents - administration & dosage
/ Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - metabolism
/ Antioxidants - administration & dosage
/ Biological Products - administration & dosage
/ Biological Products - chemistry
/ Collagen
/ Cosmeceuticals - administration & dosage
/ Coumaric Acids - administration & dosage
/ Enzymes
/ Humans
/ Keratin
/ Review
