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Developing a New Stool Test for Colorectal Cancer Screening, the multitargetFIT (mtFIT)
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Journal Article
Developing a New Stool Test for Colorectal Cancer Screening, the multitargetFIT (mtFIT)
2025
Overview
Early detection of colorectal cancer (CRC) through screening is the most effective method to reduce morbidity as well as mortality from this disease. Fecal immunochemical test (FIT)-based screening has shown to be effective, especially in multi-round population-based screening. However, its sensitivity and specificity are suboptimal, leaving room for improvement. In this perspective, the development journey of a new screening test, the multitargetFIT (mtFIT), which outperforms FIT, is described from discovery down to large-scale clinical utility testing and health technology assessment.
Publisher
Springer US,Springer,Springer Nature B.V
Subject
