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In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits
by
Azando, Erick Virgile Bertrand
, Doko Allou, Sanni-yo
, Adjobimey, Tomabu
, Olounladé, Pascal Abiodoun
, Dansou, Christian Cocou
, Adoho, Akouavi Carine Chimène
, Konmy, Basile
, Alowanou, Georcelin Goué
, Baba-Moussa, Lamine
, Tchetan, Esaïe
, Adjanohoun, Adolphe
in
Acetone
/ Animals
/ anticoccidial activity
/ Anticoccidials
/ Cellular and Infection Microbiology
/ Cytokines
/ Eimeria
/ Eimeria magna
/ Eimeria media
/ Enzyme-linked immunosorbent assay
/ Health care
/ Hematology
/ Horticulture
/ Immune response
/ Immunoglobulin G
/ Interleukin 12
/ Interleukin 4
/ Leaves
/ Moringa oleifera
/ Oocysts
/ Plant extracts
/ Rabbits
/ Tumor necrosis factor-TNF
/ Vernonia amygdalina
2023
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In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits
by
Azando, Erick Virgile Bertrand
, Doko Allou, Sanni-yo
, Adjobimey, Tomabu
, Olounladé, Pascal Abiodoun
, Dansou, Christian Cocou
, Adoho, Akouavi Carine Chimène
, Konmy, Basile
, Alowanou, Georcelin Goué
, Baba-Moussa, Lamine
, Tchetan, Esaïe
, Adjanohoun, Adolphe
in
Acetone
/ Animals
/ anticoccidial activity
/ Anticoccidials
/ Cellular and Infection Microbiology
/ Cytokines
/ Eimeria
/ Eimeria magna
/ Eimeria media
/ Enzyme-linked immunosorbent assay
/ Health care
/ Hematology
/ Horticulture
/ Immune response
/ Immunoglobulin G
/ Interleukin 12
/ Interleukin 4
/ Leaves
/ Moringa oleifera
/ Oocysts
/ Plant extracts
/ Rabbits
/ Tumor necrosis factor-TNF
/ Vernonia amygdalina
2023
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In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits
by
Azando, Erick Virgile Bertrand
, Doko Allou, Sanni-yo
, Adjobimey, Tomabu
, Olounladé, Pascal Abiodoun
, Dansou, Christian Cocou
, Adoho, Akouavi Carine Chimène
, Konmy, Basile
, Alowanou, Georcelin Goué
, Baba-Moussa, Lamine
, Tchetan, Esaïe
, Adjanohoun, Adolphe
in
Acetone
/ Animals
/ anticoccidial activity
/ Anticoccidials
/ Cellular and Infection Microbiology
/ Cytokines
/ Eimeria
/ Eimeria magna
/ Eimeria media
/ Enzyme-linked immunosorbent assay
/ Health care
/ Hematology
/ Horticulture
/ Immune response
/ Immunoglobulin G
/ Interleukin 12
/ Interleukin 4
/ Leaves
/ Moringa oleifera
/ Oocysts
/ Plant extracts
/ Rabbits
/ Tumor necrosis factor-TNF
/ Vernonia amygdalina
2023
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In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits
Journal Article
In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits
2023
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Overview
The aims of this study were to determine the immune response and the anticoccidial activity induced by
and
leaves in rabbits infected with
and
.
Thirty-five-day-old rabbits, free from coccidia, were infested with 2.10
oocysts of
and
, then received the acetone extract of the leaves of
and
at different doses by oral gavage.
The inhibition of the excretion of oocysts was evaluated by the McMaster technique and the levels of cytokines (IL-4 and IL-12) and immunoglobulin IgG were assayed by the ELISA method. The
efficacy on
and
oocysts was 95.43% and 96.53% for
and
at 1000 mg/kg bw against 98% for the positive control. Interestingly the plant extracts increased the production of interleukin (IL) and immunoglobulins (Ig) compared to controls. Plasma IL-4 levels (pg/ml) in rabbits were 128.94 and 131.38; those of IL-12 (pg/ml) were 395.55 and 426.56, and then for those of IgG (μg/ml) were 14.70 and 13.94 respectively with the acetone extracts of
and
on D14 PT at 1000 mg/kg bw. This study indicates that
and
can be used as an alternative to synthetic anticoccidials. These plants could be used to increase the resistance of the immune system of rabbits to infestations of Eimeria species in rabbit farms.
Publisher
Frontiers Media SA,Frontiers Media S.A
Subject
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