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FOXP3 ＋ regulatory T cells and their functional regulation
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Journal Article
FOXP3 ＋ regulatory T cells and their functional regulation
2015
Overview
FOXP3＋ regulatory T （Treg） cells are critical in maintaining immune tolerance and homeostasis of the immune system. The molecular mechanisms underlying the stability, plasticity and functional activity of Treg cells have been much studied in recent years. Here, we summarize these intriguing findings, and provide insight into their potential use or manipulation during Treg cell therapy for the treatment of autoimmune diseases, graft-versus-host disease （GVHD） and cancer.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
