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Mendelian randomisation, lipids, and cardiovascular disease
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Mendelian randomisation, lipids, and cardiovascular disease
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Journal Article
Mendelian randomisation, lipids, and cardiovascular disease
2012
Overview
[...]the genetic instrument should be sufficiently strongly associated with the intermediate phenotype to avoid weak instrument bias.6 The LIPG variant used here had a fairly large effect on HDL cholesterol, but is rare in the population and so might not represent a strong instrument.
Publisher
Elsevier Ltd,Elsevier Limited
