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Interferon Gamma-1b Compared with Placebo in Metastatic Renal-Cell Carcinoma

by Chin, Joe , Morales, Alvaro , Bajamonde, Alex , Saad, Fred , Venner, Peter , Gleave, Martin E , Klotz, Laurence H , Elhilali, Mostafa , Paton, Virginia , Ernst, Scott , Sanders, Coree , Ramsey, Ernest , Fradet, Yves , Moore, Malcolm J , Bell, David , Martins, Heidi , Davis, Ian

in Biological and medical sciences / Cancer therapies / Drug therapy / Health sciences / Immunomodulators / Interferon / Medical sciences / Pharmacology. Drug treatments / Skin cancer

1998

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Interferon Gamma-1b Compared with Placebo in Metastatic Renal-Cell Carcinoma

in Biological and medical sciences / Cancer therapies / Drug therapy / Health sciences / Immunomodulators / Interferon / Medical sciences / Pharmacology. Drug treatments / Skin cancer

1998

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Interferon Gamma-1b Compared with Placebo in Metastatic Renal-Cell Carcinoma

in Biological and medical sciences / Cancer therapies / Drug therapy / Health sciences / Immunomodulators / Interferon / Medical sciences / Pharmacology. Drug treatments / Skin cancer

1998

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Journal Article

Interferon Gamma-1b Compared with Placebo in Metastatic Renal-Cell Carcinoma

Chin, Joe,

Morales, Alvaro,

Bajamonde, Alex,

Saad, Fred,

Venner, Peter,

Gleave, Martin E,

Klotz, Laurence H,

Elhilali, Mostafa,

Paton, Virginia,

Ernst, Scott,

Sanders, Coree,

Ramsey, Ernest,

Fradet, Yves,

Moore, Malcolm J,

Bell, David,

Martins, Heidi,

Davis, Ian

1998

Overview

Renal-cell carcinoma is the 10th most common cancer in Western countries, with about 30,600 new cases diagnosed and 12,000 deaths from the disease in the United States during 1996. 1 Surgical resection of localized disease is the only curative treatment. Approximately one third of patients present with metastatic disease, which is incurable except in a few patients who undergo surgical excision of a solitary soft-tissue metastasis. The median duration of survival of patients with metastatic renal-cell carcinoma is about one year, and only 10 percent survive beyond two years. 2 The results remain poor because of resistance to conventional therapies, such as . . .

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Publisher

Massachusetts Medical Society

Subject

Biological and medical sciences