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Functional Dynamics of Arginine Mono- and Di-Methylation
by
Zhu, Bin
, Lu, Shanfa
, Wang, Hengbin
, Wang, Xi’ang
, Winn, Robert
in
Amino acids
/ Animals
/ Antibodies
/ Arginine
/ Arginine - metabolism
/ arginine methylation
/ Cell culture
/ Chromatography
/ Dehydrogenases
/ di-methylation
/ Disease
/ Enzymes
/ Humans
/ Labeling
/ Localization
/ Mass spectrometry
/ Methylation
/ Methyltransferases
/ mono-methylation
/ Peptides
/ Physical properties
/ Physiology
/ Post-translation
/ Post-translational modification
/ PRMTs
/ Protein Processing, Post-Translational
/ Protein-Arginine N-Methyltransferases - metabolism
/ Proteins
/ Proteomics
/ Review
/ Scientific imaging
/ Signal transduction
/ Substrate Specificity
2025
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Functional Dynamics of Arginine Mono- and Di-Methylation
by
Zhu, Bin
, Lu, Shanfa
, Wang, Hengbin
, Wang, Xi’ang
, Winn, Robert
in
Amino acids
/ Animals
/ Antibodies
/ Arginine
/ Arginine - metabolism
/ arginine methylation
/ Cell culture
/ Chromatography
/ Dehydrogenases
/ di-methylation
/ Disease
/ Enzymes
/ Humans
/ Labeling
/ Localization
/ Mass spectrometry
/ Methylation
/ Methyltransferases
/ mono-methylation
/ Peptides
/ Physical properties
/ Physiology
/ Post-translation
/ Post-translational modification
/ PRMTs
/ Protein Processing, Post-Translational
/ Protein-Arginine N-Methyltransferases - metabolism
/ Proteins
/ Proteomics
/ Review
/ Scientific imaging
/ Signal transduction
/ Substrate Specificity
2025
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Do you wish to request the book?
Functional Dynamics of Arginine Mono- and Di-Methylation
by
Zhu, Bin
, Lu, Shanfa
, Wang, Hengbin
, Wang, Xi’ang
, Winn, Robert
in
Amino acids
/ Animals
/ Antibodies
/ Arginine
/ Arginine - metabolism
/ arginine methylation
/ Cell culture
/ Chromatography
/ Dehydrogenases
/ di-methylation
/ Disease
/ Enzymes
/ Humans
/ Labeling
/ Localization
/ Mass spectrometry
/ Methylation
/ Methyltransferases
/ mono-methylation
/ Peptides
/ Physical properties
/ Physiology
/ Post-translation
/ Post-translational modification
/ PRMTs
/ Protein Processing, Post-Translational
/ Protein-Arginine N-Methyltransferases - metabolism
/ Proteins
/ Proteomics
/ Review
/ Scientific imaging
/ Signal transduction
/ Substrate Specificity
2025
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Journal Article
Functional Dynamics of Arginine Mono- and Di-Methylation
2025
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Overview
Arginine methylation is a crucial post-translational modification (PTM) that plays a significant role in various biological processes. It occurs in two primary forms: mono-methylation (MMA) and di-methylation (DMA), with the latter further classified into symmetric (SDMA) and asymmetric methylation (ADMA). This review examines the functional implications of these methylation states, current detection methodologies, proteomics-based analytical approaches, and the different impacts of these methylations on protein function. Finally, the role of protein arginine methyltransferases (PRMTs) and their substrate specificity in shaping the arginine methylome are discussed.
Publisher
MDPI AG,MDPI
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