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Unravelling nuclear size control
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Journal Article
Unravelling nuclear size control
2019
Overview
Correlation between nuclear and cell size, the nucleocytoplasmic ratio, is a cellular phenomenon that has been reported throughout eukaryotes for more than a century but the mechanisms that achieve it are not well understood. Here, we review work that has shed light on the cellular processes involved in nuclear size control. These studies have implicated nucleocytoplasmic transport, LINC complexes, RNA processing, regulation of nuclear envelope expansion and partitioning of importin α in nuclear size control, moving us closer to a mechanistic understanding of this phenomenon.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
Active Transport, Cell Nucleus
/ Animals
/ Biomedical and Life Sciences
/ Cell Nucleus Size - genetics
/ Cell Nucleus Size - physiology
/ Embryos
/ Genetics
/ Humans
/ Microbial Genetics and Genomics
/ Nuclear Envelope - metabolism
/ Review
/ RNA
/ RNA, Long Noncoding - genetics
/ RNA, Long Noncoding - metabolism
/ Schizosaccharomyces - genetics
/ Yeast
