Asset Details
Do you wish to reserve the book?
A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise
Do you wish to request the book?
A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise
2025
Overview
Sympathetic restraint in exercising muscle is currently viewed as required to prevent ‘excess’ vasodilatation from exceeding the cardiac output (Q̇ ${\\dot{Q}} $ ) response, even in submaximal exercise. Certainly, muscle vasodilatory capacity dictates the requirement for sympathetic restraint when cardiac pumping capacity is approached. However, a similar role in submaximal exercise has at least two important implications for integrated cardiovascular control in exercise that have not been considered. First, such a role means that there is a ‘set’ Q̇ ${\\dot{Q}} $response to a given exercise challenge that dictates the cardiovascular circuit flow and therefore the vasodilatation allowed such that Q̇ ${\\dot{Q}} $ –peripheral blood flow balance and target arterial blood pressure are achieved. This represents a ‘cardiocentric’ model of integrated cardiovascular control, whereby the heart leads and the peripheral resistance vessel tone is modulated accordingly. Second, what is commonly described as ‘tight’ matching of exercising muscle oxygen delivery relative to demand would therefore require that the Q̇ ${\\dot{Q}} $response is closely ‘calibrated’ to exercising muscle metabolic demand. This would require a means of driving cardiac activation via precise communication of exercising muscle metabolic demand. However, considerable evidence demonstrates that ‘excess’ vasodilatation in a healthy system simply leads to a matching increased Q̇ ${\\dot{Q}} $without arterial blood pressure compromise. This review re‐examines the evidence for existence of sympathetic restraint in exercising muscle and its currently proposed role. We propose that key questions remain unanswered and that renewed investigation into sympathetic restraint and its role can lead to important advances in understanding integrated cardiovascular control in exercise. What is the topic of this review? This review examines the current proposed role of sympathetic restraint in exercising muscle, i.e., to prevent ‘excess’ vasodilatation from exceeding the cardiac output response, even in submaximal exercise. What advances does it highlight? This review points out two implications of the current proposed role of sympathetic restraint that have been ignored. It also identifies important evidence suggesting that the current view might be incorrect.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley
