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Feasibility study of laser-driven neutron sources for pharmaceutical applications
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Journal Article
Feasibility study of laser-driven neutron sources for pharmaceutical applications
2023
Overview
We predict the production yield of a medical radioisotope
^{67}$
Cu using
^{67}$
Zn(n, p)
^{67}$
Cu and
^{68}$
Zn(n, pn)
^{67}$
Cu reactions with fast neutrons provided from laser-driven neutron sources. The neutrons were generated by the p+
^9\\mathrm{Be}$
and d+
^9$
Be reactions with high-energy ions accelerated by laser–plasma interaction. We evaluated the yield to be (3.3
$\\pm$
0.5)
$\\times$
10
^5$
atoms for
^{67}$
Cu, corresponding to a radioactivity of 1.0
$\\pm$
0.2 Bq, for a Zn foil sample with a single laser shot. Using a simulation with this result, we estimated
^{67}$
Cu production with a high-frequency laser. The result suggests that it is possible to generate
^{67}$
Cu with a radioactivity of 270 MBq using a future laser system with a frequency of 10 Hz and 10,000-s radiation in a hospital.
Publisher
Cambridge University Press
