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Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care
by
Chan, Sara S. W.
, Chan, Pang‐Fai
, Lo, Ling
, Hung, Sandra W. S.
, Chao, David V. K.
, Mak, Chui‐Ling
in
ambulatory blood pressure monitoring
/ Blood Pressure
/ Blood Pressure Monitoring, Ambulatory
/ Cardiovascular disease
/ Cardiovascular Diseases - diagnosis
/ Cardiovascular Diseases - epidemiology
/ Cerebrovascular disease
/ Chi-square test
/ China - epidemiology
/ Chinese
/ Circadian Rhythm
/ Clinics
/ Ethnicity
/ Heart attacks
/ Heart failure
/ Humans
/ Hyperlipidemia
/ Hypertension
/ Hypertension - diagnosis
/ Hypertension - epidemiology
/ Ischemia
/ Kidney diseases
/ Medical prognosis
/ Mortality
/ Nocturnal Blood Pressure Dipping
/ Original Paper
/ Patients
/ Primary care
/ Primary Health Care
/ Prognosis
/ Retrospective Studies
/ Sleep
/ Transient ischemic attack
2021
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Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care
by
Chan, Sara S. W.
, Chan, Pang‐Fai
, Lo, Ling
, Hung, Sandra W. S.
, Chao, David V. K.
, Mak, Chui‐Ling
in
ambulatory blood pressure monitoring
/ Blood Pressure
/ Blood Pressure Monitoring, Ambulatory
/ Cardiovascular disease
/ Cardiovascular Diseases - diagnosis
/ Cardiovascular Diseases - epidemiology
/ Cerebrovascular disease
/ Chi-square test
/ China - epidemiology
/ Chinese
/ Circadian Rhythm
/ Clinics
/ Ethnicity
/ Heart attacks
/ Heart failure
/ Humans
/ Hyperlipidemia
/ Hypertension
/ Hypertension - diagnosis
/ Hypertension - epidemiology
/ Ischemia
/ Kidney diseases
/ Medical prognosis
/ Mortality
/ Nocturnal Blood Pressure Dipping
/ Original Paper
/ Patients
/ Primary care
/ Primary Health Care
/ Prognosis
/ Retrospective Studies
/ Sleep
/ Transient ischemic attack
2021
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Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care
by
Chan, Sara S. W.
, Chan, Pang‐Fai
, Lo, Ling
, Hung, Sandra W. S.
, Chao, David V. K.
, Mak, Chui‐Ling
in
ambulatory blood pressure monitoring
/ Blood Pressure
/ Blood Pressure Monitoring, Ambulatory
/ Cardiovascular disease
/ Cardiovascular Diseases - diagnosis
/ Cardiovascular Diseases - epidemiology
/ Cerebrovascular disease
/ Chi-square test
/ China - epidemiology
/ Chinese
/ Circadian Rhythm
/ Clinics
/ Ethnicity
/ Heart attacks
/ Heart failure
/ Humans
/ Hyperlipidemia
/ Hypertension
/ Hypertension - diagnosis
/ Hypertension - epidemiology
/ Ischemia
/ Kidney diseases
/ Medical prognosis
/ Mortality
/ Nocturnal Blood Pressure Dipping
/ Original Paper
/ Patients
/ Primary care
/ Primary Health Care
/ Prognosis
/ Retrospective Studies
/ Sleep
/ Transient ischemic attack
2021
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Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care
Journal Article
Prognostic value of nocturnal blood pressure dipping on cardiovascular outcomes in Chinese patients with hypertension in primary care
2021
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Overview
Meta‐analyses showed that non‐dipping of nocturnal blood pressure on ambulatory blood pressure monitoring (ABPM) was associated with adverse cardiovascular prognosis. However, these prognostic studies were mainly conducted in Caucasian and Japanese populations. Whether this association applies to Chinese patients remained uninvestigated. A total of 1199 Chinese patients with hypertension undergoing ABPM between January 2012 and December 2014 were recruited retrospectively from five public hypertension referral clinics in Hong Kong. Patients were followed up for a mean 6.42 years for cardiovascular morbidity and mortality and all‐cause mortality. Time to event of different dipping patterns was compared by Kaplan‐Meier curves. Hazard ratios (HR) were obtained by Cox proportional hazard models with patient demographics and confounding factors adjusted in multivariate regression. A total of 163 end point events occurred in the period. Normal dipping was observed in 446 patients (37.2%), non‐dipping in 490 (40.9%), reverse dipping in 161 (13.4%), and extreme dipping in 102 (8.5%). Kaplan‐Meier analyses showed inferior survival in non‐dippers and reverse dippers for total cardiovascular events and coronary events but not cerebrovascular events. After adjusting for confounding factors, Cox regressions showed HRs 1.166 (CI 0.770‐1.764) and 1.173 (CI 0.681‐2.021) in non‐dippers and reverse dippers for total cardiovascular events, and HRs 1.320 (CI 0.814‐2.141) and 1.476 (CI 0.783‐2.784) for coronary events. Nocturnal blood pressure non‐dipping, and to a greater extent reverse dipping, demonstrated adverse cardiovascular prognosis in a cohort of Chinese patients with hypertension in Hong Kong. Further focused studies on cerebrovascular events and reverse dippers were warranted to refine risk stratification.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley
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