Journal Article

Center experience and other determinants of patient radiation exposure during prostatic artery embolization: a retrospective study in three Scandinavian centers

Kløw, Nils-Einar, Lönn, Lars Birger, Waltenburg, Hanne, Svarc, Petra, Baco, Eduard, Taudorf, Mikkel, Hagen, Thijs, Andersson, Christian, Røder, Martin Andreas, Lindgren, Hans, Bläckberg, Mats

2022

Overview

Objectives To evaluate the effects of center experience and a variety of patient- and procedure-related factors on patient radiation exposure during prostatic artery embolization (PAE) in three Scandinavian centers with different PAE protocols and levels of experience. Understanding factors that influence radiation exposure is crucial in effective patient selection and procedural planning. Methods Data were collected retrospectively for 352 consecutive PAE procedures from January 2015 to June 2020 at the three centers. Dose area product (DAP (Gy·cm 2 )) was selected as the primary outcome measure of radiation exposure. Multiple patient- and procedure-related explanatory variables were collected and correlated with the outcome variable. A multiple linear regression model was built to determine significant predictors of increased or decreased radiation exposure as reflected by DAP. Results There was considerable variation in DAP between the centers. Intended unilateral PAE ( p  = 0.03) and each 10 additional patients treated ( p  = 0.02) were significant predictors of decreased DAP. Conversely, increased patient body mass index (BMI, p  < 0.001), fluoroscopy time ( p  < 0.001), and number of digital subtraction angiography (DSA) acquisitions ( p  < 0.001) were significant predictors of increased DAP. Conclusions To minimize patient radiation exposure during PAE radiologists may, in collaboration with clinicians, consider unilateral embolization, pre-interventional CTA for procedure planning, using predominantly anteroposterior (AP) projections, and limiting the use of cone-beam CT (CBCT) and fluoroscopy. Key Points • Growing center experience and intended unilateral embolization decrease patient radiation exposure during prostatic artery embolization. • Patient BMI, fluoroscopy time, and number of DSA acquisitions are associated with increased DAP during procedures. • Large variation in radiation exposure between the centers may reflect the use of CTA before and CBCT during the procedure.

• Publisher: Springer Berlin Heidelberg,Springer Nature B.V
• Subject: Angiography / Angiography, Digital Subtraction - methods / Arteries - diagnostic imaging / Body mass / Body mass index / Body size / Clinical Medicine / Diagnostic Radiology / Embolization / Embolization, Therapeutic - methods / Exposure / Fluoroscopy / Humans / Imaging / Internal Medicine / Interventional Radiology / Klinisk medicin / Male / Medical and Health Sciences / Medicin och hälsovetenskap / Medicine / Medicine & Public Health / Neuroradiology / Prostate - blood supply / Prostate - diagnostic imaging / Prostatic Hyperplasia - diagnostic imaging / Prostatic Hyperplasia - therapy / Radiation / Radiation Dosage / Radiation effects / Radiation Exposure / Radiation measurement / Radiologi och bildbehandling / Radiology / Radiology and Medical Imaging / Regression models / Retrospective Studies / Ultrasound / Vascular-Interventional