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A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells
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A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells
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Journal Article
A New Fluorescent Probe for Hydrogen Sulfide Detection in Solution and Living Cells
2023
Overview
Since Hydrogen Sulfide (H2S) was recognized as a gas transmitter, its detection and quantification have become a hot research topic among chemists and biologists. In this area, fluorescent probes have shown great advantages: fast and strong response, low detection limit and easy manipulation. Here we developed a new fluorescent probe that detected H2S selectively among various bioactive and inorganic salts. This probe was based on the core structure of fluorescein and reacted with H2S through azide-reduction. Great linearity was achieved correlating fluorescence intensity and H2S concentrations in solution. The detection of H2S in cancer cells was also achieved.
Publisher
MDPI AG,MDPI
