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Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation

by Argenziano, Michael , Goldstein, Daniel , Acker, Michael A , Parides, Michael K , Dagenais, Francois , Bagiella, Emilia , Geller, Nancy L , Rose, Eric A , Taddei-Peters, Wendy C , Voisine, Pierre , Overbey, Jessica R , Ailawadi, Gorav , Thourani, Vinod , O’Sullivan, Karen , O’Gara, Patrick T , Mack, Michael , Williams, Deborah L , Gelijns, Annetine C , Hung, Judy W , Perrault, Louis P , Kron, Irving L , Michler, Robert E , Miller, Marissa A , Atluri, Pavan , Smith, Peter K , Gammie, James S , Demers, Philippe , Weisel, Richard D , Moskowitz, Alan J , Gillinov, A. Marc , Moquete, Ellen

in Cardiovascular disease / Clinical outcomes / Heart / Heart diseases / Heart Failure - etiology / Heart surgery / Heart Valve Prosthesis Implantation / Heart Ventricles - anatomy & histology / Heart Ventricles - physiopathology / Hospitalization / Humans / Ischemia / Mitral Valve - surgery / Mitral Valve Insufficiency - complications / Mitral Valve Insufficiency - mortality / Mitral Valve Insufficiency - surgery / Patients / Quality of Life / Recurrence / Regurgitation / Reoperation - statistics & numerical data / Surgery / Survival / Treatment Failure / Ventricle / Ventricular Function, Left / Ventricular Remodeling

2016

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2016

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2016

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Journal Article

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation

Argenziano, Michael,

Goldstein, Daniel,

Acker, Michael A,

Parides, Michael K,

Dagenais, Francois,

Bagiella, Emilia,

Geller, Nancy L,

Rose, Eric A,

Taddei-Peters, Wendy C,

Voisine, Pierre,

Overbey, Jessica R,

Ailawadi, Gorav,

Thourani, Vinod,

O’Sullivan, Karen,

O’Gara, Patrick T,

Mack, Michael,

Williams, Deborah L,

Gelijns, Annetine C,

Hung, Judy W,

Perrault, Louis P,

Kron, Irving L,

Michler, Robert E,

Miller, Marissa A,

Atluri, Pavan,

Smith, Peter K,

Gammie, James S,

Demers, Philippe,

Weisel, Richard D,

Moskowitz, Alan J,

Gillinov, A. Marc,

Moquete, Ellen

2016

Overview

Among patients with severe ischemic mitral regurgitation who were assigned to mitral-valve repair or replacement, there were no significant between-group differences in left ventricular remodeling or mortality at 2 years. Mitral regurgitation recurred more frequently in the repair group. Ischemic mitral regurgitation is a serious consequence of coronary artery disease that carries a substantial risk of death from cardiovascular causes in proportion to its severity. 1 , 2 Ischemic mitral regurgitation is anatomically characterized by remodeling or distortion of left ventricular geometry that ultimately results in papillary-muscle displacement, leaflet tethering, and impaired coaptation. For the subgroup of patients with severe ischemic mitral regurgitation, the prognosis is grave, with rates of death ranging from 15 to 40% at 1 year. 2 – 4 For patients with severe ischemic mitral regurgitation, the benefit of surgical revascularization is undisputed, provided that the patient has suitable coronary . . .

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Publisher

Massachusetts Medical Society

Subject

Cardiovascular disease

/ Clinical outcomes

/ Heart

/ Heart diseases

/ Heart Failure - etiology

/ Heart surgery

/ Heart Valve Prosthesis Implantation