Asset Details
Do you wish to reserve the book?
Effects of Fentanyl and Low Doses of Alcohol on Neuropsychological Performance in Healthy Subjects
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effects of Fentanyl and Low Doses of Alcohol on Neuropsychological Performance in Healthy Subjects
Do you wish to request the book?
Effects of Fentanyl and Low Doses of Alcohol on Neuropsychological Performance in Healthy Subjects
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effects of Fentanyl and Low Doses of Alcohol on Neuropsychological Performance in Healthy Subjects
1999
Overview
The effects of the opioid fentanyl and low doses of alcohol on neuropsychological functions in healthy volunteers were measured. Twenty-four healthy male volunteers participated in this study. Two randomised placebo-controlled cross-over trials were conducted. In group 1, 6 subjects received fentanyl (0.2 µg/kg body weight) in the order of fentanyl/placebo and 6 subjects in the order of placebo/fentanyl. Group 2 received alcohol in a similar procedure by continuous intravenous infusion, leading to a blood alcohol concentration (BAC) of 0.03%. Impairment was measured via different neuropsychological tests. The results indicate that fentanyl in concentrations commonly used in out-patient surgical procedures produces pronounced cognitive impairment (auditory reaction time, signal detection, sustained attention, recognition) in comparison to placebo. After application of low doses of alcohol (BAC 0.03%) only visual reaction time was impaired in comparison to placebo.
Publisher
Karger,S. Karger AG
Subject
/ Analgesics, Opioid - pharmacology
/ Biological and medical sciences
/ Biological Psychology/PharmacopsychologyMain Editor: P. Netter (Giessen)Original Paper
/ Central Nervous System Depressants - pharmacology
/ Drug toxicity and drugs side effects treatment
/ Humans
/ Male
/ Pharmacology. Drug treatments
/ Psychomotor Performance - drug effects
/ Reaction Time - drug effects
