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Journal Article
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2019
Overview
Penile Carcinoma In a large series involving 89 men with invasive penile squamous cell carcinoma (SCC) without palpable inguinal disease, Ramos et al. have reported the diagnostic precision of sentinel lymph node biopsy (SLNB). For the entire cohort, the authors have reported that dynamic SLNB had a sensitivity of 84%, a specificity of 89%, and a false-negative rate of 6.6%, with a similarity ratio (LR+) of 7.80 (3.80–16.03) and a likelihood ratio (LR−) of 0.18 (0.07–0.44). [...]when the authors have calculated the sensitivity and specificity only for high-risk T1 patients, who required superficial inguinal lymphadenectomy according to the current NCCN guidelines, the sensitivity was 33% and the specificity 100% for such subgroup of patients, along with a positive predictive value of 100%, a negative predictive value of 93%, and a diagnostic accuracy of 93.9%.
Publisher
Wolters Kluwer India Pvt. Ltd,Medknow Publications and Media Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Wolters Kluwer - Medknow,Wolters Kluwer Medknow Publications
Subject
