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Reply to ‘Evolutionary stasis of viruses?’
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Journal Article

Reply to ‘Evolutionary stasis of viruses?’

2019
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Overview
In their recent Opinion article (Prisoners of war — host adaptation and its constraints on virus evolution. Nat. Rev. Microbiol. https://doi.org/10.1038/s41579-018-0120-2 (2018))1, Simmonds et al. use studies of hepatitis B virus (HBV)2 and B19 parvovirus3 from Bronze Age remains, along with endogenous viruses4, to propose that evolutionary rates in viruses decline massively as they adapt to hosts. Although these data have changed our perspective on evolutionary timescales, we disagree that they predict long-term evolutionary stasis.
Publisher
Nature Publishing Group