Asset Details
Do you wish to reserve the book?
MRI techniques to measure arterial and venous cerebral blood volume
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
MRI techniques to measure arterial and venous cerebral blood volume
Do you wish to request the book?
MRI techniques to measure arterial and venous cerebral blood volume
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
MRI techniques to measure arterial and venous cerebral blood volume
2019
Overview
The measurement of cerebral blood volume (CBV) has been the topic of numerous neuroimaging studies. To date, however, most in vivo imaging approaches can only measure CBV summed over all types of blood vessels, including arterial, capillary and venous vessels in the microvasculature (i.e. total CBV or CBVtot). As different types of blood vessels have intrinsically different anatomy, function and physiology, the ability to quantify CBV in different segments of the microvascular tree may furnish information that is not obtainable from CBVtot, and may provide a more sensitive and specific measure for the underlying physiology. This review attempts to summarize major efforts in the development of MRI techniques to measure arterial (CBVa) and venous CBV (CBVv) separately. Advantages and disadvantages of each type of method are discussed. Applications of some of the methods in the investigation of flow-volume coupling in healthy brains, and in the detection of pathophysiological abnormalities in brain diseases such as arterial steno-occlusive disease, brain tumors, schizophrenia, Huntington's disease, Alzheimer's disease, and hypertension are demonstrated. We believe that the continual development of MRI approaches for the measurement of compartment-specific CBV will likely provide essential imaging tools for the advancement and refinement of our knowledge on the exquisite details of the microvasculature in healthy and diseased brains.
•To date, most CBV MRI methods measure total CBV.•Arterial and venous blood vessels are intrinsically different.•Here, MRI methods for CBVa and CBVv measurement are reviewed.•Compartment specific flow-volume coupling is investigated using the methods.•Applications of the methods in brain diseases are demonstrated.
Publisher
Elsevier Inc,Elsevier Limited
Subject
/ Animals
/ Blood
/ Brain Diseases - diagnostic imaging
/ Brain Diseases - physiopathology
/ CBV
/ Cerebral Arteries - diagnostic imaging
/ Cerebral Cortex - blood supply
/ Cerebral Cortex - diagnostic imaging
/ Cerebral Veins - diagnostic imaging
/ Humans
/ Magnetic Resonance Imaging - methods
/ MRI
/ Vein
/ Venule
