Journal Article

Clinical Impact of Dysglycemia in Patients with an Acute Myocardial Infarction

Nam, Jong-Ho, Son, Jang-Won, Won, Kyu-Chang, Lee, Chan-Hee, Kim, Ung, Chung, Jae-Wook, Park, Jong-Seon, Shin, Dong-Gu, Seo, Jeong-Eon, Lee, Jung-Hee, Park, Yeong-Seon, Oh, Cheol-Woo, Son, Yeseul

2021

Overview

This study aimed to determine the impact of dysglycemia on myocardial injury and cardiac dysfunction in acute myocardial infarctions (AMIs). From 2005 to 2016, a total of 1,593 patients with AMIs who underwent percutaneous coronary intervention were enrolled. The patients were classified into five groups according to the admission glucose level: ≤80, 81 to 140, 141 to 200, 201 to 260, and ≥261 mg/dL. The clinical and echocardiographic parameters and 30-day mortality were analyzed. The peak troponin I and white blood cell levels had a positive linear relationship to the admission glucose level. The left ventricular ejection fraction had an inverted U-shape trend, and the E/E' ratio was U-shaped based on euglycemia. The 30-day mortality also increased as the admission glucose increased, and the cut-off value for predicting the mortality was 202.5 mg/dL. Dysglycemia, especially hyperglycemia, appears to be associated with myocardial injury and could be another adjunctive parameter for predicting mortality in patients with AMIs.

• Publisher: Korean Diabetes Association / Daehan Dangnyobyeong Hakoe,Korean Diabetes Association,대한당뇨병학회
• Subject: Brief Report / Cardiac function / Conflicts of interest / Diabetes / diabetes mellitus / Glucose / Heart attacks / Humans / Hyperglycemia / Hyperglycemia - complications / Hypoglycemia / Ischemia / Mortality / myocardial infarction / Myocardial Infarction - complications / Retrospective Studies / Stroke Volume / Ventricular Function, Left / 내과학