Asset Details
Do you wish to reserve the book?
Early Diagnosis, Early Stratification, and Early Intervention to Deliver Precision Medicine in IBD
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Early Diagnosis, Early Stratification, and Early Intervention to Deliver Precision Medicine in IBD
Do you wish to request the book?
Early Diagnosis, Early Stratification, and Early Intervention to Deliver Precision Medicine in IBD
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Early Diagnosis, Early Stratification, and Early Intervention to Deliver Precision Medicine in IBD
2022
Overview
Abstract
Despite huge advances in understanding the molecular basis of IBD, clinical management has continued to rely on a “trial and error” approach. In addition, a therapeutic ceiling has emerged whereby even the most effective interventions are only beneficial for approximately 30% of patients. Consequently, several tools have been developed to aid stratification and guide treatment-decisions.
We review the potential application for many of these precision medicine approaches, which are now almost within reach. We highlight the importance of early action (and avoiding inaction) to ensure the best outcomes for patients and how combining early action with precision tools will likely ensure the right treatment is delivered at the right time and place for each individual person living with IBD.
The lack of clinical impact to date from precision medicine, despite much hype and investment, should be tempered with the knowledge that clinical translation can take a long time, and many promising breakthroughs might be ready for clinical implementation in the near future. We discuss some of the remaining challenges and barriers to overcome for clinical adoption. We also highlight that early recognition, early diagnosis, early stratification, and early intervention go hand in hand with precision medicine tools. It is the combination of these approaches that offer the greatest opportunity to finally deliver on the promise of precision medicine in IBD.
Lay Summary
Several precision medicine tools to guide treatment decisions are almost ready for clinical implementation. We highlight that combining these tools with a focus on early action offers the greatest opportunity to finally deliver on the promise of precision medicine in IBD.
Publisher
Oxford University Press,Lippincott, Williams & Wilkins
