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Risks of Stroke and Transient Cerebral Ischemia up to 4 Years Post-SARS-CoV-2 Infection in Large Diverse Urban Population in the Bronx
by
Hadidchi, Roham
, Rahmani, Liora
, Duong, Tim Q.
, Vichare, Aditi
, Henry, Sonya
, Changela, Sagar
in
Asthma
/ Cerebral ischemia
/ cerebrovascular risks
/ Chronic obstructive pulmonary disease
/ Cohort analysis
/ Comorbidity
/ COVID-19 outcomes
/ COVID-19 vaccines
/ Electronic health records
/ Ethnicity
/ Health aspects
/ Hospitalization
/ Hypertension
/ Immunization
/ Insurance coverage
/ Ischemia
/ ischemic stroke
/ Kidney diseases
/ Medicaid
/ Medical research
/ Medicare
/ Medicine, Experimental
/ Patients
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Stroke
/ Stroke (Disease)
/ transient cerebral ischemia
/ Urban population
/ Viral infections
2025
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Risks of Stroke and Transient Cerebral Ischemia up to 4 Years Post-SARS-CoV-2 Infection in Large Diverse Urban Population in the Bronx
by
Hadidchi, Roham
, Rahmani, Liora
, Duong, Tim Q.
, Vichare, Aditi
, Henry, Sonya
, Changela, Sagar
in
Asthma
/ Cerebral ischemia
/ cerebrovascular risks
/ Chronic obstructive pulmonary disease
/ Cohort analysis
/ Comorbidity
/ COVID-19 outcomes
/ COVID-19 vaccines
/ Electronic health records
/ Ethnicity
/ Health aspects
/ Hospitalization
/ Hypertension
/ Immunization
/ Insurance coverage
/ Ischemia
/ ischemic stroke
/ Kidney diseases
/ Medicaid
/ Medical research
/ Medicare
/ Medicine, Experimental
/ Patients
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Stroke
/ Stroke (Disease)
/ transient cerebral ischemia
/ Urban population
/ Viral infections
2025
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Risks of Stroke and Transient Cerebral Ischemia up to 4 Years Post-SARS-CoV-2 Infection in Large Diverse Urban Population in the Bronx
by
Hadidchi, Roham
, Rahmani, Liora
, Duong, Tim Q.
, Vichare, Aditi
, Henry, Sonya
, Changela, Sagar
in
Asthma
/ Cerebral ischemia
/ cerebrovascular risks
/ Chronic obstructive pulmonary disease
/ Cohort analysis
/ Comorbidity
/ COVID-19 outcomes
/ COVID-19 vaccines
/ Electronic health records
/ Ethnicity
/ Health aspects
/ Hospitalization
/ Hypertension
/ Immunization
/ Insurance coverage
/ Ischemia
/ ischemic stroke
/ Kidney diseases
/ Medicaid
/ Medical research
/ Medicare
/ Medicine, Experimental
/ Patients
/ Risk factors
/ SARS-CoV-2
/ Severe acute respiratory syndrome coronavirus 2
/ Statistical analysis
/ Stroke
/ Stroke (Disease)
/ transient cerebral ischemia
/ Urban population
/ Viral infections
2025
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Risks of Stroke and Transient Cerebral Ischemia up to 4 Years Post-SARS-CoV-2 Infection in Large Diverse Urban Population in the Bronx
Journal Article
Risks of Stroke and Transient Cerebral Ischemia up to 4 Years Post-SARS-CoV-2 Infection in Large Diverse Urban Population in the Bronx
2025
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Overview
Background: SARS-CoV-2 infection could trigger hypercoagulation and hyperinflammation that may predispose patients to cerebrovascular events. The long-term risk of stroke among COVID-19 patients remains unclear. This study investigated the long-term risks of ischemic stroke and transient cerebral ischemia (TCI) among patients with and without COVID-19. Methods: We conducted an observational cohort study in the Montefiore Health System (February 2020–January 2024), with 52,117 COVID+ and 837,395 COVID− patients without prior cerebrovascular events. Demographics, comorbidities, insurance, unmet social needs, and median income were adjusted for using inverse probability weighting. Cox-proportional regression hazard ratios (HR) and their 95% confidence intervals were computed for ischemic stroke and TCI. Results: Compared to COVID− controls, ischemic stroke risk was higher among hospitalized COVID+ patients (HR = 1.32 [1.12–1.55]) and non-hospitalized COVID+ patients (1.21 [1.05–1.39]). Compared to COVID− controls, TCI risk was similar among hospitalized COVID+ patients (1.00 [0.75–1.33]), but higher among non-hospitalized COVID+ patients (2.15 [1.81–2.56]). Conclusions: Hospitalized and non-hospitalized COVID-19 patients had a higher long-term risk of ischemic stroke while only non-hospitalized COVID-19 patients had a higher long-term risk of TCI. These findings underscore the needs for long-term monitoring of cerebrovascular risk factors in COVID-19 survivors.
Publisher
MDPI AG,Multidisciplinary Digital Publishing Institute (MDPI)
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