Asset Details
Do you wish to reserve the book?
Wallerian degeneration in cervical spinal cord tracts is commonly seen in routine T2-weighted MRI after traumatic spinal cord injury and is associated with impairment in a retrospective study
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Wallerian degeneration in cervical spinal cord tracts is commonly seen in routine T2-weighted MRI after traumatic spinal cord injury and is associated with impairment in a retrospective study
Do you wish to request the book?
Wallerian degeneration in cervical spinal cord tracts is commonly seen in routine T2-weighted MRI after traumatic spinal cord injury and is associated with impairment in a retrospective study
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Wallerian degeneration in cervical spinal cord tracts is commonly seen in routine T2-weighted MRI after traumatic spinal cord injury and is associated with impairment in a retrospective study
2021
Overview
Objectives
Wallerian degeneration (WD) is a well-known process after nerve injury. In this study, occurrence of remote intramedullary signal changes, consistent with WD, and its correlation with clinical and neurophysiological impairment were assessed after traumatic spinal cord injury (tSCI).
Methods
In 35 patients with tSCI, WD was evaluated by two radiologists on T2-weighted images of serial routine MRI examinations of the cervical spine. Dorsal column (DC), lateral corticospinal tract (CS), and lateral spinothalamic tract (ST) were the analyzed anatomical regions. Impairment scoring according to the American Spinal Injury Association Impairment Scale (AIS, A–D) as well as a scoring system (0–4 points) for motor evoked potential (MEP) and sensory evoked potential (SEP) was included. Mann-Whitney
U
test was used to test for differences.
Results
WD in the DC occurred in 71.4% (
n
= 25), in the CS in 57.1% (
n
= 20), and in 37.1% (
n
= 13) in the ST. With WD present, AIS grades were worse for all tracts. DC: median AIS B vs D,
p
< 0.001; CS: B vs D,
p
= 0.016; and ST: B vs D,
p
= 0.015. More pathological MEP scores correlated with WD in the DC (median score 0 vs 3,
p
< 0.001) and in the CS (0 vs 2,
p
= 0.032). SEP scores were lower with WD in the DC only (1 vs 2,
p
= 0.031).
Conclusions
WD can be detected on T2-weighted scans in the majority of cervical spinal cord injury patients and should be considered as a direct effect of the trauma. When observed, it is associated with higher degree of impairment.
Key Points
• Wallerian degeneration is commonly seen in routine MRI after traumatic spinal cord injury.
• Wallerian degeneration is visible in the anatomical regions of the dorsal column, the lateral corticospinal tract, and the lateral spinothalamic tract.
• Presence of Wallerian degeneration is associated with higher degree of impairment.
Publisher
Springer Berlin Heidelberg,Springer Nature B.V
Subject
Cervical Cord - diagnostic imaging
/ Humans
/ Imaging
/ Medicine
/ Neuro
/ Pyramidal Tracts - diagnostic imaging
/ Pyramidal Tracts - pathology
/ Spinal Cord - diagnostic imaging
/ Spinal Cord Injuries - complications
/ Spinal Cord Injuries - diagnostic imaging
/ Spinal Cord Injuries - pathology
/ Trauma
