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Thermally Drawn Polymeric Catheters for MR‐Guided Cardiovascular Intervention
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Thermally Drawn Polymeric Catheters for MR‐Guided Cardiovascular Intervention
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Journal Article
Thermally Drawn Polymeric Catheters for MR‐Guided Cardiovascular Intervention
2024
Overview
Cardiovascular diseases (CVDs), including congenital heart diseases (CHD), present significant global health challenges, emphasizing the need for safe and effective treatment modalities. Fluoroscopy‐guided endovascular interventions are widely utilized but raise concerns about ionizing radiation, especially in pediatric cases. Magnetic resonance imaging (MRI) offers a radiation‐free alternative with superior soft tissue visualization and functional insights. However, the lack of compatible instruments remains a major obstacle. An adapted thermal drawing platform that enables low‐cost and rapid prototyping of instruments for MR‐guided endovascular interventions is introduced. This platform is demonstrated through the development of two exemplary catheter systems: a tendon‐driven steerable catheter with helical lumina and an active tracking Tiger‐shaped catheter with an embedded coaxial wire. These catheters exhibit mechanical properties comparable to commercial counterparts and show promising outcomes in both in vitro and in vivo feasibility testing. This scalable thermal drawing platform addresses the limitations of existing manufacturing approaches and facilitates the exploration of diverse designs, potentially accelerating advancements in catheter technologies for MR‐guided cardiovascular interventions. This research presents an adapted thermal drawing platform for cost‐effective and rapid prototyping of catheters for MR‐guided endovascular interventions. The benefits of the proposed platform are demonstrated in the development of advanced catheter systems, exhibiting excellent mechanical properties and MR visibility. Successful in vitro and in vivo testing underscores their potential for advanced cardiovascular procedures under MR guidance.
Publisher
John Wiley & Sons, Inc,John Wiley and Sons Inc,Wiley
Subject
/ Cardiovascular Diseases - therapy
/ cardiovascular interventions
/ catheter
/ Design
/ Endovascular Procedures - instrumentation
/ Endovascular Procedures - methods
/ Geometry
/ Humans
/ Magnetic Resonance Imaging - methods
/ Magnetic Resonance Imaging, Interventional - instrumentation
/ Magnetic Resonance Imaging, Interventional - methods
/ MRI
/ Wire
