Journal Article

Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm

Dea, Nicolas, Fisher, Charles G., Laufer, Ilya, Shin, John H., Leary, Owen P., Hornicek, Francis J., Sahgal, Arjun, Boriani, Stefano, Gong, Jung Ho, Gokaslan, Ziya L., Fridley, Jared S., Gasbarrini, Alessandro, Setty, Aayush, Goodwin, Matthew L., Cecchinato, Riccardo, Lazáry, Áron, Bettegowda, Chetan, Ali, Rohaid, Reynolds, Jeremy J., Verlaan, Jorrit-Jan, Luzzati, Alessandro, Rhines, Laurence D., Mesfin, Addisu

2025

Overview

Study Design Narrative Review. Objective Contextualized by a narrative review of recent literature, we propose a wound complication prevention and management algorithm for spinal oncology patients. We highlight available strategies and motivate future research to identify optimal and individualized wound management for this population. Methods We conducted a search of recent studies (2010-2022) using relevant keywords to identify primary literature in support of current strategies for wound complication prevention and management following spine tumor surgery. When primary literature specific to spine tumor cases was not available, data were extrapolated from studies of other spine surgery populations. Results were compiled into a proposed clinical algorithm to guide practice considering available evidence. Results Based on available literature, we recommend individualized stratification of patients according to identifiable risk factors for wound complication and propose several interventions which might be employed preventatively, including intrawound antibiotic administration, negative pressure wound therapy, and primary flap closure of the surgical wound. Of these, the available evidence, weighing possible risks vs benefits, most strongly favors primary flap closure of surgical wounds, particularly for patients with multiple risk factors. A secondary algorithm to guide management of wound complications is also proposed. Conclusions Wound complications such as SSI and dehiscence remain a significant source of morbidity following spine tumor surgery. Triaging patients on an individualized basis according to risk factors for complication may aid in selecting appropriate prophylactic strategies to prevent these complications. Future research in this area is still needed to strengthen recommendations.

• Publisher: SAGE Publications,Sage Publications Ltd,SAGE Publishing
• Subject: Algorithms / Antibiotics / Back surgery / Clinical decision making / Health risks / Special Issue / Spinal cancer / Surgical site infections