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Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

by Widge, Alicia T , Rouphael, Nadine G , Makhene, Mamodikoe , Bennett, Hamilton , Mascola, John R , Lai, Lilin , Beigel, John H , Roberts, Paul C , Graham, Barney S , Lin, Bob C , Neuzil, Kathleen M , Schmidt, Stephen D , O’Connell, Sarah , Albert, Jim , O’Dell, Sijy , Suthar, Mehul S , Flach, Britta , Edara, Venkata-Viswanadh , Anderson, Evan J , Zarnitsyna, Veronika , Leav, Brett , Ledgerwood, Julie E , Doria-Rose, Nicole , McDermott, Adrian B , Jackson, Lisa A , Luke, Catherine J , Makowski, Mat , Kunwar, Pratap , Floyd, Katharine , Buchanan, Wendy

in 2019-nCoV Vaccine mRNA-1273 / Adult / Age / Aged / Antibodies / Antibodies, Neutralizing - blood / Antibodies, Viral - blood / Coronaviruses / COVID-19 / COVID-19 - immunology / COVID-19 vaccines / COVID-19 Vaccines - immunology / Half-Life / Humans / Medical research / Middle Aged / mRNA / SARS-CoV-2 - immunology / Severe acute respiratory syndrome coronavirus 2 / Vaccination / Vaccines

2021

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Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

2021

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Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

2021

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Journal Article

Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19

Widge, Alicia T,

Rouphael, Nadine G,

Makhene, Mamodikoe,

Bennett, Hamilton,

Mascola, John R,

Lai, Lilin,

Beigel, John H,

Roberts, Paul C,

Graham, Barney S,

Lin, Bob C,

Neuzil, Kathleen M,

Schmidt, Stephen D,

O’Connell, Sarah,

Albert, Jim,

O’Dell, Sijy,

Suthar, Mehul S,

Flach, Britta,

Edara, Venkata-Viswanadh,

Anderson, Evan J,

Zarnitsyna, Veronika,

Leav, Brett,

Ledgerwood, Julie E,

Doria-Rose, Nicole,

McDermott, Adrian B,

Jackson, Lisa A,

Luke, Catherine J,

Makowski, Mat,

Kunwar, Pratap,

Floyd, Katharine,

Buchanan, Wendy

2021

Overview

A total of 33 participants who received both doses of the Moderna mRNA-1273 vaccine against SARS-CoV-2 had blood drawn over a period of 6 months after vaccination. SARS-CoV-2 neutralizing activity was maintained in all the patients through the entire period of follow-up. A half-life of 202 days was determined for the live-virus neutralization activity.

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Publisher

Massachusetts Medical Society

Subject

2019-nCoV Vaccine mRNA-1273

/ Adult

/ Age

/ Aged

/ Antibodies

/ Antibodies, Neutralizing - blood

/ Antibodies, Viral - blood