Asset Details
Do you wish to reserve the book?
High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation
Do you wish to request the book?
High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation
2022
Overview
High flow nasal cannula (HFNC) may improve CO2 elimination by washing out CO2 from the upper airways. This study aimed at assessing the effect of HFNC on minute ventilation and ventilatory ratio (VR), a surrogate of dead space, in patients hospitalized for acute hypercapnic COPD exacerbation.
Physiological study comparing HFNC at 40 L/min to low flow oxygen. Variations of tidal volume (VT) and minute ventilation between the two treatments were estimated from chest plethysmography. Respiratory rate (RR) and arterial blood gases were measured. Variations in VR were calculated. Data were compared using Wilcoxon tests.
Recordings performed in 10 patients. Minute ventilation was reduced with HFNC by −16.2 [−30.9–0.4] % (p = 0.049). VT was not different but RR was lower during HFNC. PaCO2 was lower with HFNC compared to standard oxygen: 48.7 [46.4–58.1] vs 50.7 [48.4–57.5] mmHg (p = 0.020). VR decreased by −18.0 [−34.7 - -4.0] % (p = 0.020) with HFNC.
In patients recovering from acute COPD exacerbation, the use of HFNC reduced RR, minute ventilation, PaCO2 and VR compared to standard oxygen. These changes are consistent with a decrease in physiologic dead space with HFNC.
•High flow nasal canula improves breathing efficiency in hypercapnic COPD exacerbation.•High flow nasal canula reduces ventilatory ratio, a surrogate of dead space in COPD exacerbation.•High flow nasal canula can be of interest during non invasive ventilation interruptions.
Publisher
Elsevier Inc,Elsevier Limited,WB Saunders
