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The role of adult hippocampal neurogenesis in brain health and disease
by
Gage, Fred H
, Toda, Tomohisa
, Parylak, Sarah L
, Linker, Sara B
in
Brain health
/ Dentate gyrus
/ Environmental changes
/ Hippocampus
/ Mental health
/ Mood disorders
/ Neurogenesis
/ Neurological diseases
/ Physiology
2019
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Do you wish to request the book?
The role of adult hippocampal neurogenesis in brain health and disease
by
Gage, Fred H
, Toda, Tomohisa
, Parylak, Sarah L
, Linker, Sara B
in
Brain health
/ Dentate gyrus
/ Environmental changes
/ Hippocampus
/ Mental health
/ Mood disorders
/ Neurogenesis
/ Neurological diseases
/ Physiology
2019
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The role of adult hippocampal neurogenesis in brain health and disease
Journal Article
The role of adult hippocampal neurogenesis in brain health and disease
2019
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Overview
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating evidence suggests that adult-born neurons may play distinct physiological roles in hippocampus-dependent functions, such as memory encoding and mood regulation. In addition, several brain diseases, such as neurological diseases and mood disorders, have deleterious effects on adult hippocampal neurogenesis, and some symptoms of those diseases can be partially explained by the dysregulation of adult hippocampal neurogenesis. Here we review a possible link between the physiological functions of adult-born neurons and their roles in pathological conditions.
Publisher
Nature Publishing Group
Subject
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