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Xishaeleganins A–D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans
by
Wang, Chang-Yun
, Zhao, Qingmin
, Lan, Lefu
, Guo, Yue-Wei
, Gu, Yu-Cheng
, Chen, Bao
in
Animals
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - isolation & purification
/ Anti-Bacterial Agents - pharmacology
/ antibacterial
/ Antibacterial activity
/ antibacterial properties
/ Antibiotics
/ Carbon
/ Dactylospongia elegans
/ hydroquinone
/ Hydroquinones - chemistry
/ Hydroquinones - isolation & purification
/ Hydroquinones - pharmacology
/ Marine invertebrates
/ Metabolites
/ Microbial Sensitivity Tests
/ Minimum inhibitory concentration
/ Porifera
/ Porifera - chemistry
/ sesquiterpene hydroquinones
/ Sesquiterpenes - chemistry
/ Sesquiterpenes - isolation & purification
/ Sesquiterpenes - pharmacology
/ sesquiterpenoids
/ spectral analysis
/ Spectrum Analysis
/ sponge
/ Staphylococcus aureus
/ Staphylococcus aureus - drug effects
/ Thorectida
/ Vancomycin
/ Vancomycin - pharmacology
2022
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Xishaeleganins A–D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans
by
Wang, Chang-Yun
, Zhao, Qingmin
, Lan, Lefu
, Guo, Yue-Wei
, Gu, Yu-Cheng
, Chen, Bao
in
Animals
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - isolation & purification
/ Anti-Bacterial Agents - pharmacology
/ antibacterial
/ Antibacterial activity
/ antibacterial properties
/ Antibiotics
/ Carbon
/ Dactylospongia elegans
/ hydroquinone
/ Hydroquinones - chemistry
/ Hydroquinones - isolation & purification
/ Hydroquinones - pharmacology
/ Marine invertebrates
/ Metabolites
/ Microbial Sensitivity Tests
/ Minimum inhibitory concentration
/ Porifera
/ Porifera - chemistry
/ sesquiterpene hydroquinones
/ Sesquiterpenes - chemistry
/ Sesquiterpenes - isolation & purification
/ Sesquiterpenes - pharmacology
/ sesquiterpenoids
/ spectral analysis
/ Spectrum Analysis
/ sponge
/ Staphylococcus aureus
/ Staphylococcus aureus - drug effects
/ Thorectida
/ Vancomycin
/ Vancomycin - pharmacology
2022
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Xishaeleganins A–D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans
by
Wang, Chang-Yun
, Zhao, Qingmin
, Lan, Lefu
, Guo, Yue-Wei
, Gu, Yu-Cheng
, Chen, Bao
in
Animals
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - isolation & purification
/ Anti-Bacterial Agents - pharmacology
/ antibacterial
/ Antibacterial activity
/ antibacterial properties
/ Antibiotics
/ Carbon
/ Dactylospongia elegans
/ hydroquinone
/ Hydroquinones - chemistry
/ Hydroquinones - isolation & purification
/ Hydroquinones - pharmacology
/ Marine invertebrates
/ Metabolites
/ Microbial Sensitivity Tests
/ Minimum inhibitory concentration
/ Porifera
/ Porifera - chemistry
/ sesquiterpene hydroquinones
/ Sesquiterpenes - chemistry
/ Sesquiterpenes - isolation & purification
/ Sesquiterpenes - pharmacology
/ sesquiterpenoids
/ spectral analysis
/ Spectrum Analysis
/ sponge
/ Staphylococcus aureus
/ Staphylococcus aureus - drug effects
/ Thorectida
/ Vancomycin
/ Vancomycin - pharmacology
2022
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Xishaeleganins A–D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans
Journal Article
Xishaeleganins A–D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans
2022
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Overview
Four new sesquiterpene hydroquinones, xishaeleganins A–D (6–9), along with eleven known related ones (12 and 14–23) were isolated from the Xisha marine sponge Dactylospongia elegans (family Thorectida). Their structures were determined by extensive spectroscopic analysis, ECD calculations, and by comparison with the spectral data reported in the literature. Compounds 7, 15, 20, and 21 showed significant antibacterial activity against Staphylococcus aureus, with minimum inhibitory concentration values of 1.5, 2.9, 5.6, and 5.6 µg/mL, which are comparable with those obtained for the positive control vancomycin (MIC: 1.0 µg/mL).
Publisher
MDPI AG,MDPI
Subject
/ Anti-Bacterial Agents - chemistry
/ Anti-Bacterial Agents - isolation & purification
/ Anti-Bacterial Agents - pharmacology
/ Carbon
/ Hydroquinones - isolation & purification
/ Hydroquinones - pharmacology
/ Minimum inhibitory concentration
/ Porifera
/ Sesquiterpenes - isolation & purification
/ Sesquiterpenes - pharmacology
/ sponge
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