Asset Details
Do you wish to reserve the book?
Comparison of thromboelastography with routine laboratory coagulation parameters to assess the hemostatic profile and prognosticate postoperative critically ill patients
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Comparison of thromboelastography with routine laboratory coagulation parameters to assess the hemostatic profile and prognosticate postoperative critically ill patients
Do you wish to request the book?
Comparison of thromboelastography with routine laboratory coagulation parameters to assess the hemostatic profile and prognosticate postoperative critically ill patients
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Comparison of thromboelastography with routine laboratory coagulation parameters to assess the hemostatic profile and prognosticate postoperative critically ill patients
2021
Overview
Background: Patients undergoing surgery often demonstrate coagulopathy. Usually, this derangement in coagulation is assessed by the laboratory based evaluation of blood samples. However, collection of samples, their transportation to the lab, and the analyses can result in several errors and as such these tests may not be representative of the complete coagulation process. In our study, we compared the lab coagulation parameters with the point of care TEG indices and attempted to compare the outcome prediction of our patients based on the TEG indices and the various practiced ICU scores.
Methods: A prospective, observational study was conducted between May 2014 and May 2015. Fifty adult patients who had undergone noncardiac surgery and had developed new onset 2 or more than 2 system involvement in the postoperative period were enrolled in the study. They were sampled simultaneously for lab coagulation parameters (PT, APTT, INR, fibrinogen, and platelet count) and TEG on days 1, 3, and 5 post admission.
Results: There were significant differences between TEG and lab coagulation parameters on day 1 of the study 1 (P = 0.004) but not on days 3 and 5. On days 1 and 3 of our study, the ICU scores (SOFA and APACHE II) were significantly higher in the group with deranged TEG parameters (P = 0.003, 0.02). The patient subpopulation with deranged TEG parameters had significantly higher mortality at median survival time (P = 0.014). Such a difference was not found in patients with higher ICU scores or deranged lab coagulation times. We constructed a ROC curve and arrived at a cutoff value of the reaction time to predict the median survival day mortality.
Conclusions: The agreement between TEG and conventional lab parameters remains poor but the TEG parameters seem to be more deranged in sicker patients. As the relationship between the overall severity of illness and derangement in the hemostatic system has been well explored in medical literature, TEG may be a more appropriate modality in such patients.
Publisher
Wolters Kluwer India Pvt. Ltd,Medknow Publications & Media Pvt. Ltd,Wolters Kluwer - Medknow,Wolters Kluwer Medknow Publications
Subject
