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Contractile Properties of the Human Diaphragm during Chronic Hyperinflation
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Journal Article
Contractile Properties of the Human Diaphragm during Chronic Hyperinflation
1991
Overview
HYPERINFLATION of the lungs impairs the function of the diaphragm by placing it at mechanical disadvantage, shortening its operating length, and changing the mechanical linkage between its various parts. These factors decrease the tension that can be developed and the amount of transdiaphragmatic pressure produced in response to a given tension.
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Furthermore, as lung volume increases, the fraction of transdiaphragmatic pressure that can be applied to the lungs with a resultant fall in transpulmonary pressure decreases.
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The action of the diaphragm may thus be altered in patients with chronic obstructive pulmonary disease (COPD) and may contribute to their disability and . . .
Publisher
Massachusetts Medical Society
