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Revisiting the therapeutic potential of gingerols against different pharmacological activities

by Kumar, Lokender , Anal, Jasha Momo H. , Shukla, Monu Kumar , Sharma, Samridhi , Bhattacharyya, Sanjib , Sharma, Krishan Chander , Kumar, Deepak , Tirath , Upadhyay, Santosh Kumar

in Alzheimer's disease / Antioxidants / Apoptosis / Archives & records / Arthritis / Biomedical and Life Sciences / Biomedicine / Cancer / Catechols - pharmacology / Catechols - therapeutic use / Cell cycle / Cell division / Chronic pain / Diabetes mellitus / Essential oils / Fatty Alcohols - chemistry / Fatty Alcohols - pharmacology / Fatty Alcohols - therapeutic use / Flavors / Menstruation / Metabolic disorders / Nausea / Neurodegenerative diseases / Neurosciences / Osteoarthritis / Pharmaceutical sciences / Pharmacology / Pharmacology/Toxicology / Phenolic compounds / Plant Extracts - chemistry / Resins / Review / Rheumatoid arthritis / Rhizomes / Zingiber officinale - chemistry / Zingiber officinale - metabolism

2023

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Revisiting the therapeutic potential of gingerols against different pharmacological activities

by Kumar, Lokender , Anal, Jasha Momo H. , Shukla, Monu Kumar , Sharma, Samridhi , Bhattacharyya, Sanjib , Sharma, Krishan Chander , Kumar, Deepak , Tirath , Upadhyay, Santosh Kumar

2023

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Revisiting the therapeutic potential of gingerols against different pharmacological activities

by Kumar, Lokender , Anal, Jasha Momo H. , Shukla, Monu Kumar , Sharma, Samridhi , Bhattacharyya, Sanjib , Sharma, Krishan Chander , Kumar, Deepak , Tirath , Upadhyay, Santosh Kumar

2023

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Journal Article

Revisiting the therapeutic potential of gingerols against different pharmacological activities

Kumar, Lokender,

Anal, Jasha Momo H.,

Shukla, Monu Kumar,

Sharma, Samridhi,

Bhattacharyya, Sanjib,

Sharma, Krishan Chander,

Kumar, Deepak,

Tirath,

Upadhyay, Santosh Kumar

2023

Overview

The rhizomes of ginger have been in use in many forms of traditional and alternative medicines. Besides being employed as condiment and flavoring agent, it is used in the treatment of nausea, osteoarthritis, muscle pain, menstrual pain, chronic indigestion, Alzheimer’s disease, and cancer. Ginger rhizome contains volatile oils, phenolic compounds and resins, and characterization studies showed that [6]-gingerol, [6]-shogaol, and [6]-paradol are reported to be the pharmacologically active components. Gingerol is a major chemical constituent found as volatile oil in the rhizomes of ginger. It has several medicinal benefits and used for the treatment of rheumatoid arthritis, nausea, cancer, and diabetes. Many studies have been carried out in various parts of the world to isolate and standardize gingerol for their use as a complementary medicine. The present review summarizes wide range of research studies on gingerol and its pharmacological roles in various metabolic diseases. Graphical Abstract

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Publisher

Springer Berlin Heidelberg,Springer Nature B.V

Subject

/ Biomedical and Life Sciences

/ Biomedicine