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The aryl hydrocarbon receptor and the gut–brain axis
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Journal Article
The aryl hydrocarbon receptor and the gut–brain axis
2021
Overview
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor initially identified as the receptor for dioxin. Almost half a century after its discovery, AHR is now recognized as a receptor for multiple physiological ligands, with important roles in health and disease. In this review, we discuss the role of AHR in the gut–brain axis and its potential value as a therapeutic target for immune-mediated diseases.
Publisher
Nature Publishing Group
Subject
