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Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature

by Khan, Erum , Shrestha, Ashish K , Liberio, Richard N , Shitiz, Sriwastava , Colantonio, Mark A

in Case reports / Coronaviruses / COVID-19 / COVID-19 vaccines / Guillain-Barre syndrome / Immunization / Inflammatory diseases / Literature reviews / Magnetic resonance imaging / Meningoencephalitis / Myelitis / Neurology / Plasmapheresis / Severe acute respiratory syndrome coronavirus 2 / Spinal cord / Vaccination

2022

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Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature

by Khan, Erum , Shrestha, Ashish K , Liberio, Richard N , Shitiz, Sriwastava , Colantonio, Mark A

2022

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Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature

by Khan, Erum , Shrestha, Ashish K , Liberio, Richard N , Shitiz, Sriwastava , Colantonio, Mark A

2022

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Journal Article

Acute transverse myelitis following SARS-CoV-2 vaccination: a case report and review of literature

Khan, Erum,

Shrestha, Ashish K,

Liberio, Richard N,

Shitiz, Sriwastava,

Colantonio, Mark A

2022

Overview

ObjectiveTo report a unique case and literature review of post COVID-19 vaccination associated transverse myelitis and with abnormal MRI findings.BackgroundCoronavirus disease have been reported to be associated with several neurological manifestations such as stroke, Guillain-Barré syndrome, meningoencephalitis amongst others. There are only a few reported cases of transverse myelitis with the novel coronavirus (n-CoV-2). Here, we identify a post COVID-19 vaccination patient diagnosed with acute transverse myelitis.MethodA retrospective chart review of a patient diagnosed with post SARS-CoV-2 vaccination acute transverse myelitis, and a review of literature of all the reported cases of other post vaccination and transverse myelitis, from December 1st, 2010 till July 15th, 2021, was performed.ConclusionTo our knowledge, this is the one of early reported case of transverse myelitis and with post SARS-CoV-2 vaccination, who responded well to plasmapheresis. Further studies would be recommended to identify the underlying correlation between COVID-19 vaccination and transverse myelitis.

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Publisher

Springer Nature B.V

Subject

/ Guillain-Barre syndrome

/ Immunization

/ Inflammatory diseases