Asset Details

MbrlCatalogueTitleDetail

Do you wish to reserve the book?

siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities

by Yang, Xin , Zheng, Libin , Liu, Huilin , Wang, Mina , Ge, Xiaobo , Zhai, Miaoxin , Cheng, Xiaoyu , Dai, Yidan , Sun, Jingqing , Li, Bin , Yuan, Fang , Wei, Jiangyan , Li, Wenshan , Liu, Guannan , Liu, Lu

in Adenosine / Anterior cruciate ligament / Apoptosis / Biosynthesis / Body fat / Bone marrow / Cartilage / Cartilage diseases / Chronic diseases / Clinical trials / Cytokines / Diagnosis / Extracellular matrix / Gene expression / Health aspects / Homeostasis / Immune response / Inflammation / Knee / Long-term effects / Medical research / MicroRNAs / Non-coding RNA / Non-coding RNAs / Osteoarthritis / Pathogenesis / Post-transcription / Post-translation / Proteases / Protein synthesis / Proteins / Quality of life / Review / Ribosomal RNAs / Roles / siRNA / Small interfering RNAs / Stem cells / Synovium / Transfer RNA / Transfer RNAs

2025

Yes Please

Hey, we have placed the reservation for you!

By the way, why not check out events that you can attend while you pick your title.

Oops! Something went wrong.

Looks like we were not able to place the reservation. Kindly try again later.

Are you sure you want to remove the book from the shelf?

siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities

2025

Confirm

Do you wish to request the book?

siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities

2025

Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy

How would you like to get it?

Submit

We have requested the book for you!

Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.

Oops! Something went wrong.

Looks like we were not able to place your request. Kindly try again later.

Journal Article

siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities

Yang, Xin,

Zheng, Libin,

Liu, Huilin,

Wang, Mina,

Ge, Xiaobo,

Zhai, Miaoxin,

Cheng, Xiaoyu,

Dai, Yidan,

Sun, Jingqing,

Li, Bin,

Yuan, Fang,

Wei, Jiangyan,

Li, Wenshan,

Liu, Guannan,

Liu, Lu

2025

Overview

Osteoarthritis (OA) is a prevalent chronic disease, characterized by progressive joint degeneration and primarily affects older adults. OA leads to reduced functional abilities, a lower quality of life, and an increased mortality rate. Currently, effective treatment options for OA are lacking. Non-coding RNAs (ncRNAs) are functional RNAs transcribed from DNA but not translated into proteins. Among ncRNAs, small interfering RNAs (siRNAs), transfer RNAs (tRNAs), and ribosomal RNAs (rRNAs) have become significant in the field, which is intricately linked to the progression of OA and perform significant regulatory functions in transcription, post-transcription, and post-translation, making them potential biological targets for the prevention, diagnosis, and treatment of OA. This review summarizes the general functions of siRNAs, tRNAs, and rRNAs and their application in OA. The primary focus has been on regulating cartilage degradation. Other participations include regulating synovium, protecting anterior cruciate ligament cells, and diagnosis. No clinical trials were found as challenges such as effective delivery systems, immune responses, long-term effects, and interactions between therapies need to be demonstrated first.

Share this book

Add to My Shelf

Publisher

Dove Medical Press Limited,Taylor & Francis Ltd,Dove Press,Dove Medical Press

Subject

Adenosine

/ Anterior cruciate ligament